Sökning: "radiation biology"
Visar resultat 11 - 15 av 143 avhandlingar innehållade orden radiation biology.
11. Lutetium-177-octreotate treatment of small intestine neuroendocrine tumors - Radiation biology as basis for optimization
Sammanfattning : Patients with neuroendocrine tumors (NETs) often have metastatic spread at the time of diagnosis. NETs frequently express somatostatin receptors (SSTR) that can be targeted by radiolabeled somatostatin analogs (e.g. 177Lu-octreotate). LÄS MER
12. Optimizing experimental radioimmunotherapy : investigating the different mechanisms behind radiation induced cell deaths
Sammanfattning : Background. Radiation therapy is an important treatment regimen for malignant disease. Radiation therapy uses ionizing radiation to induce DNA damage in tumor cells in order to kill them. LÄS MER
13. Accurate description of heterogeneous tumors for biologically optimized radiation therapy
Sammanfattning : In this thesis, a model of tissue oxygenation is presented, that takes into account the heterogeneous nature of tumor vasculature. Even though the model is rather simple, the resulting oxygen distributions agree very well with clinically observed oxygen distributions for most tumors and healthy normal tissues. LÄS MER
14. Radiation induced biomarkers of individual sensitivity to radiation therapy
Sammanfattning : Fifty percent of solid cancers are treated with radiation therapy (RT). The dose used in RT is adjusted to the most sensitive individuals so that not more than 5% of the patients will have severe adverse healthy tissue effects. LÄS MER
15. Measurement of sensitivity to DNA damaging agents
Sammanfattning : There is a large inter-individual variation in intrinsic sensitivity in patients receiving treatment with DNA damaging agents. Cancer therapy exemplifies this problem where patients experience varying degree of normal tissue side effects in response to radiation or chemotherapy. LÄS MER