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Visar resultat 11 - 15 av 56 avhandlingar som matchar ovanstående sökkriterier.

  1. 11. Systemic sclerosis. Novel molecular and epidemiological features of disease

    Författare :Kristofer Andréasson; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic sclerosis; fibrosis; COMP; calprotectin; biomarker; gastrointestinal;

    Sammanfattning : Systemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. LÄS MER

  3. 12. Idiopathic pulmonary fibrosis : disease presentation, clinical course and potential biomarkers

    Författare :Dimitrios Kalafatis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The interest and research within the area of the fatal lung disease idiopathic pulmonary fibrosis (IPF) has increased exponentially over the past decades. This has resulted in important insights into the nature and pathogenesis of the disease, which ultimately constitute the knowledge base upon which diagnostic, management, treatment decisions and guidelines are shaped. LÄS MER

  4. 13. Airway mechanics of mice and men

    Författare :Lennart Lundblad; Malmö Klinisk fysiologi och nuklearmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; radiologi; tomografi; tomography; medical instrumentation; Clinical physics; Medicin människa och djur ; Medicine human and vertebrates ; Penh; emphysema; airway resistance; gas conditioning; plethysmography; lung mechanics; Boyle s law; Physiology; medicinsk instrumentering; Klinisk fysiologi; radiology; enhanced pause; pulmonary fibrosis; micro computed tomography; forced oscillation technique; COPD;

    Sammanfattning : In this thesis we explore and further develop several techniques used in the animal laboratory as well as in the clinical setting. In particular, we expand the understanding and usefulness of plethysmographic techniques in small rodents. LÄS MER

  5. 14. Remodeling of airway epithelium and lung extracellular matrix in COPD and IPF

    Författare :Ulf Hedström; Lungbiologi; []
    Nyckelord :Chronic obstructive pulmonary disease; Idiopathic pulmonary fibrosis; Extracellular matrix; Epithelial cells; Remodeling;

    Sammanfattning : .... LÄS MER

  7. 15. Skin fibrosis, internal organ involvement and auto antibodies in systemic sclerosis: longitudinal development and impact on survival

    Författare :Roger Hesselstrand; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Skeleton; proteoglycan; pulmonary hypertension; organ involvement; auto antibodies; survival; systemic sclerosis; prognosis;

    Sammanfattning : Systemic sclerosis (SSc) is a connective tissue disease with a highly variable prognosis. Since new treatment strategies are emerging, there is a need for prognostic markers in order to help allocate patients to the optimal treatment. LÄS MER