Sökning: "Malmö Klinisk fysiologi och nuklearmedicin"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Malmö Klinisk fysiologi och nuklearmedicin.
1. Aspects of PET-CT in prostate cancer. Protocol optimization, diagnostic accuracy, and dosimetry
Sammanfattning : The PET-CT imaging modality is based on positron emission tomography combined with computed tomography. Before a PET-CT examination, a radioactive tracer (also called a radiopharmaceutical) is intravenously injected into the patient. PET technology images the distribution of this tracer element by detecting the decay. LÄS MER
2. Deposition and absorption of inhaled drugs
Sammanfattning : Main objectives of this thesis were to evaluate a gamma scintigraphic method used to quantify drug aerosol deposition in the lung, to investigate the influence of two aerosol inhalation parameters on the distribution of inhaled dry powder within the airways, to assess pulmonary absorption kinetics and bioavailability of an inhaled hydrophilic solute in relation to site of deposition, and to assess the influence of a surface active agent (sodium taurocholate, a bile salt) on the deposition and absorption of an inhaled hydrophilic solute. Repeated planar gamma scintigraphy was found to provide the same information on total pulmonary drug deposition as an independent method that involved assessments of urinary drug recovery after blockage of gastrointestinal drug absorption when all of the critical parts of the methodological procedures were accurately and meticulously executed. LÄS MER
3. Airway mechanics of mice and men
Sammanfattning : In this thesis we explore and further develop several techniques used in the animal laboratory as well as in the clinical setting. In particular, we expand the understanding and usefulness of plethysmographic techniques in small rodents. LÄS MER
4. Arterial wall stiffness in man. On gender differences and abnormalities in insulin dependent diabetes mellitus and alpha1-antitrypsin deficiency
Sammanfattning : The mechanical properties of major arteries may reflect early manifestations of vascular disease and are also of interest because they are important for cardiac work. Using echo-tracking sonography and blood pressure measurements, arterial stiffness and diameters were investigated in healthy individuals as well as in patients with insulin dependent diabetes mellitus (IDDM) or alpha1-antitrypsin deficiency (alpha1-AT deficiency). LÄS MER
5. Daily Physical Activity, Body Fat and Aerobic Fitness in Children
Sammanfattning : Introduction: Physical inactivity, low aerobic fitness and obesity are all associated with an increased risk of a wide range of diseases in adults. Promotion of physical activity, improvement of aerobic fitness and regulation of body weight in children may be of importance, as low physical activity, low aerobic fitness and obesity early in life have been known to track into adulthood. LÄS MER