Sökning: "auto antibodies"
Visar resultat 1 - 5 av 36 avhandlingar innehållade orden auto antibodies.
1. Diabetes mellitus in Adults - Aspects of Incidence, Autoimmunity and C-peptide
Sammanfattning : Type 1 and type 2 diabetes increase worldwide, leading to a heavy burden of disease and its complications. All 1666 adults aged 18-100 years with new onset diabetes in Kronoberg during 3 years were registered, and type of diabetes classified by pancreatic autoantibodies and C-peptide. LÄS MER
2. Skin fibrosis, internal organ involvement and auto antibodies in systemic sclerosis: longitudinal development and impact on survival
Sammanfattning : Systemic sclerosis (SSc) is a connective tissue disease with a highly variable prognosis. Since new treatment strategies are emerging, there is a need for prognostic markers in order to help allocate patients to the optimal treatment. LÄS MER
3. The Role of Fc gamma Receptors and Mast Cell Chymase in Autoimmune Arthritis
Sammanfattning : In autoimmune diseases such as rheumatoid arthritis (RA), self-reactive antibodies are present at high levels, which contributes to disease pathogenesis. The antibodies mediate their effect predominantly by binding to Fc gamma receptors (FcγR) on various leukocytes, such as monocytes, macrophages and mast cells, where FcγR ligation leads to cell activation. LÄS MER
4. Vaccine responses after chemotherapy or stem cell transplantation in patients with hematological malignancies
Sammanfattning : The prevention of infections in patients with hematological malignancies is important given the inherent immune deficiency associated with these diseases and the immunosuppressive effects of treatment. This thesis investigated the efficacy of vaccines against various pathogens among patients with hematological disease receiving chemotherapy or stem cell transplantation, including the longevity of vaccine responses. LÄS MER
5. Preclinical Molecular Imaging using Multi-Isotope Digital Autoradiography - Techniques and Applications
Sammanfattning : Molecular imaging, both in vivo and ex vivo, is playing an increasingly important role in preclinical medical research. When using radionuclide-labeled tracers, e.g. in the development of radiopharmaceuticals for diagnostic imaging or for radionuclide therapy, quantitative in vivo imaging can be performed using emission tomography. LÄS MER