Sökning: "proteinuria"

Visar resultat 6 - 10 av 67 avhandlingar innehållade ordet proteinuria.

1. 6. Physiological and morphological aspects of the glomerular barrier in health and disease. Results based on experimental studies in the rat

   Författare :Clara Hjalmarsson; Göteborgs universitet; []
   Nyckelord :glomerular permeability; isolated perfused kidney; charge; endothelial surface layer; glycocalyx; electron microscopy; orosomucoid; nephrotic syndrome; proteinuria;

   Sammanfattning : Tremendous amounts of fluid are filtered every day through the kidneys. The anastomosing capillary loops surrounded by Bowman s capsule, forming the glomerulus, function in accordance with the interplay between the hydrostatic and the colloid osmotic pressure. The result of the action of these mechanisms is the production of primary urine. LÄS MER

3. 7. Membranous Nephropathy - Challenges in diagnostics and treatment

   Författare :Jennie Lönnbro-Widgren; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glomerulonephritis; Membranous nephropathy; Proteinuria; Phospholipase A2 receptor; Cancer; End-stage renal disease;

   Sammanfattning : The variability in the pathogenesis, clinical presentation and outcome of membranous nephropathy (MN) poses major clinical challenges and raises different questions, both regarding diagnostics and treatment of patients with MN. The aims of this thesis were therefore to examine: 1) differences in the glomerular expression of different IgG subclasses and phospholipase A2 receptor (PLA2R) between patients with idiopathic and malignancy-associated MN; 2) treatment pattern of patients with idiopathic MN; and 3) if the serum PLA2R antibody level at diagnosis can be used as a prognostic marker. LÄS MER

4. 8. Endogenous proteins as markers of glomerular function and dysfunction

   Författare :Jan Tencer; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glomerular filter; amyloidosis; glomerulonephritis; glomerular disease; proteins; proteinuria; Urology; nephrology; Urologi; nefrologi;

   Sammanfattning : Plasma and urine concentrations of endogenous proteins are frequently used in the diagnosis of kidney diseases and in studies of glomerular filter function. The main issues addressed in these studies were: storage of urine samples for subsequent protein analysis, use of protein concentrations in urine and in plasma in health and as markers of glomerular diseases, and the application of renal plasma-to-urine clearance of endogenous proteins in estimating the size-selectivity properties of the glomerular capillary wall. LÄS MER

5. 9. Urinary Biomarkers and Patient Outcome in Chronic Kidney Disease and Atherosclerotic Heart Disease: The value of IgM-uria and IgG-uria

   Författare :Rafid Tofik; Njurmedicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Proteinuria; Albuminuria; urine IgM; urine IgG; glomerulonephritis; chronic kidney disease; atherosclerosis; cardiovascular disease; diabetic kidney disease.;

   Sammanfattning : Risk stratification of patients with chronic kidney disease and atherosclerotic heart disease is crucial. Microalbuminuria (MA) is associated with an increased risk of kidney and cardiovascular (CV) death, especially in patients with diabetes. LÄS MER

7. 10. Biochemical and Epidemiological Studies of Early-Onset and Late-Onset Pre-Eclampsia

   Författare :Anna-Karin Wikström; Matts Olovsson; Ulf Eriksson; Solveig Norden-Lindeberg; Göran Berg; Uppsala universitet; []
   Nyckelord :Obstetrics and gynaecology; pre-eclampsia; proteinuria; albumin-creatinine ratio; ischaemic heart disease; angiogenesis; sFlt1; oxidative stress; isoprostane; PAI-1; PAI-2; Obstetrik och kvinnosjukdomar;

   Sammanfattning : Biochemical and epidemiological aspects of pre-eclampsia were investigated, with the main focus on possible pathophysiological differences between early-onset and late-onset disease.In pre-eclamptic women poor correlation was found between albumin-creatinine ratio (ACR) in a random urine sample and total amount of albumin in a 24-hour urine collection. LÄS MER