Sökning: "proteinuria"
Visar resultat 26 - 30 av 67 avhandlingar innehållade ordet proteinuria.
26. The Role of Mitochondrial Uncoupling in the Development of Diabetic Nephropathy
Sammanfattning : Diabetes is closely associated with increased oxidative stress, especially originating from the mitochondria. A mechanism to reduce increased mitochondria superoxide production is to reduce the mitochondria membrane potential by releasing protons across the mitochondria membrane. LÄS MER
27. The role of glycoproteins in glomerular pathophysiology
Sammanfattning : Chronic kidney disease (CKD) is increasing worldwide and has a prevalence of around 10%. With time patients are at risk of losing their renal function and will need dialysis or transplantation for survival. There are no specific treatments available and mechanisms behind the onset and progression of CKD are still not fully investigated. LÄS MER
28. Regulation of Renal Hyaluronan in Water Handling : Studies in vivo and in vitro
Sammanfattning : Hyaluronan (HA) is a negatively charged extracellular matrix (ECM) component with water-attracting properties. It is the dominating ECM component in the renal medullary interstitium, where the amount changes in relation to hydration status: it increases during hydration and decreases during dehydration. LÄS MER
29. Adverse effects of exposure to air pollutants during fetal development and early life : with focus on pre-eclampsia, preterm delivery, and childhood asthma
Sammanfattning : Background Air pollution exposure has been shown to have adverse effects on several health outcomes, and numerous studies have reported associations with cardiovascular morbidity, respiratory disease, and mortality. Over the last decade, an increasing number of studies have investigated possible associations with pregnancy outcomes, including preterm delivery. LÄS MER
30. Genetic basis of congenital nephrotic syndrome and generation of an animal model
Sammanfattning : Congenital nephrotic syndrome, NPHS1, is a disease highly enriched in Finland with incidence of 1:8200 births. The disease is characterized by massive proteinuria, go % of which is albumin, starting in utero, large placenta, which weighs over 25 % of the child's birth weight, and manifestation of proteinuria soon after birth. LÄS MER