Sökning: "phagocytosis and macrophage"
Visar resultat 1 - 5 av 46 avhandlingar innehållade orden phagocytosis and macrophage.
1. Towards a detailed understanding of the red blood cell storage lesion : and its consequences for in vivo survival following transfusion
Sammanfattning : Red blood cells (RBCs) are vital for oxygen delivery to tissues and constitute the vast majority of all cells in blood. After leaving the red bone marrow as mature cells, RBCs have a lifespan of approximately 120 days before they are removed from the circulation by macrophages, mainly in the spleen and liver. LÄS MER
2. Leishmania donovani Lipophosphoglycan : Modulation of Macrophage and Dendritic Cell Function
Sammanfattning : Leishmania donovani is a blood-borne tropicial parasite, which infects humans through bites by Phlebotomus sandflies. The parasite survives and multiplies inside macrophages in inner organs, and causes the deadly disease visceral leishmaniasis (Kala-Azar). LÄS MER
3. The importance of monocyte and granulocyte activation in rheumatoid arthritis and primary Sjögren's syndrome
Sammanfattning : Macrophages and neutrophils infiltrate the synovium and synovial fluid in rheumatoid arthritis (RA). These cells are considered to contribute to the destructive process in RA.The expression of adhesion and phagocytosis receptors on the surface of peripheral granulocytes and monocytes was increased in patients with RA. LÄS MER
4. Mechanisms involved in macrophage phagocytosis of apoptotic cells
Sammanfattning : Efficient removal of apoptotic cells is critical for development, tissue remodelling, maintenance of homeostasis, and response to injury. Phagocytosis of apoptotic cells is mediated by many phagocytic receptors, soluble bridging molecules, and pro-phagocytic ligands on the surface of apoptotic cells. LÄS MER
5. Role of the CD47/SIRPα-interaction in regulation of macrophage phagocytosis
Sammanfattning : CD47 is a cell surface glycoprotein that is expressed by virtually all cells in the body. Binding of CD47 to the macrophage receptor Signal Regulatory Protein alpha (SIRPα) yields an inhibitory signal that counteracts phagocytosis. LÄS MER