Visar resultat 1 - 5 av 355 avhandlingar innehållade ordet neutrophil.
Sammanfattning : The leukocytes have, as part of their function in immune system, the ability to leave the bloodstream, penetrate the vascular wall and migrate towards extravascular targets. This behaviour of the leukocytes has been extensively studied both in vivo and in vitro since the 19th century but the mechanisms underlying leukocyte migration are not yet fully understood. LÄS MER
2. CD64 (FcγRI) Expression on Neutrophil Granulocytes : A Diagnostic Marker of Acute Bacterial Infections
Sammanfattning : Background. Newborn infants, especially preterm infants, have an increased susceptibility to serious and overwhelming bacterial as well as fungal infections. Symptoms of septicaemia in especially the very preterm neonates are vague and unspecific. LÄS MER
3. Novel findings on cellular trafficking and targeting for granule storage of neutrophil elastase, a multifunctional effector molecule of innate immunity
Sammanfattning : Neutrophil elastase (NE) has important roles in innate immunity, killing pathogens and controlling the immune response; but how NE is targeted to developing granules is not understood. Therefore, the aim of this thesis was to investigate the sorting of NE. LÄS MER
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Sammanfattning : Human neutrophils are the most abundant of the white blood cells in circulation and represent the first line of defense against invading microorganisms. With a membrane-bound enzyme system (the NADPH oxidase), these cells can generate reactive oxygen metabolites that serve efficiently in antimicrobial defense. LÄS MER