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Visar resultat 1 - 5 av 10 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Tailoring Radionuclide Therapy of Neuroendocrine Tumors - Bridging the Gaps

    Författare :Anna Sundlöv; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 177Lu-DOTATATE; PRRT; somatostatin analogs; pituitary function; renal function; dosimetry; 68Ga-DOTATATE; individualized treatment; neuroendocrine tumors;

    Sammanfattning : Background and Aims: Radionuclide therapy is systemic, targeted radiotherapy. As such, we can apply the basic principles of radiobiology used in everyday practice in radiation oncology, as a means of tailoring the treatment to each patient and optimizing the balance between efficacy and toxicity. LÄS MER

  3. 2. Prostate cancer and neuroendocrine differentiation. Molecular aspects in prostate cancer development

    Författare :Nastaran Monsef; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; neuron specific enolase; neuroendocrine differentiation; serotonin; hypoxia; cancer stem cell; synaptophysin; Gleason score; chromogranin A; Gleason grade;

    Sammanfattning : Hormone refractory prostate cancer occurs when androgen-deprivation therapy (ADT) fails to stop the growth of prostate cancer for any longer. Recent studies point towards a role for neuroendocrine (NE) differentiation in the development of hormone refractory disease. LÄS MER

  4. 3. Human motor control, autonomic and decision processes under physical and psychological stress. Instinctive, reflexive and adaptive aspects

    Författare :Johan Bertilsson; Lund näs- och halssjukdomar Öron-; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Neuroendocrine stress response; Pepper spray; Police officer involved shootings; Memory distortions; Motor control;

    Sammanfattning : The stress response is governed by automatic neurological and hormonal processes that occur before we become consciously aware of a dangerous situation. If stress ensues for 15-30 seconds, the hormonal processes may have progressed so far that recovery takes an hour or longer instead of minutes. LÄS MER

  5. 4. Immunopathological and Structural Alterations in Difficult to Control Asthma

    Författare :Anders Bergqvist; Luftvägsinflammation; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Severe asthma; bronchial thermoplasty; airway smooth muscle; neuroendocrine cells; inflammation; immune cells; remodelling;

    Sammanfattning : Asthma is a chronic respiratory disorder affecting an estimated 300 million people worldwide. Most patients with asthma can be controlled with bronchodilators and low to moderate dose inhaled corticosteroids. However, an estimated 5-10% of the population presents a more troublesome disease, often referred to as severe asthma. LÄS MER

  7. 5. Regulatory Proteins in Progenitors and Differentiated Cells of the Human Prostate

    Författare :Jens Ceder; Malmö (Abrahamsson) Urologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mesenchymal stem cells; somatostatin; transit amplifying cells; cell differentiation; adult stem cells; Prostate gland; prostatic benign hyperplasia; neuroendocrine cells; prostate cancer;

    Sammanfattning : Prostate cancer (PC) develops from an androgen-dependent tissue that contains androgen receptors in both the stromal and glandular compartments. Surgical removal of the prostate may cure the patient, but if metastatic spread has occurred, androgen suppression therapy is the standard treatment. LÄS MER