Sökning: "airway smooth muscle"

Visar resultat 1 - 5 av 39 avhandlingar innehållade orden airway smooth muscle.

  1. 1. The hyperosmolar airway : Mechanisms of reduced response to nitric oxide

    Författare :Josephine Hjoberg; Uppsala universitet; []
    Nyckelord :Medical sciences; 8-Br-cyclic GMP; airway epithelium; airway reactivity; airway smooth muscle; amiloride; epithelium derived relaxing factor; furosemide; hyperosmolarity; hypertonic saline; nitric oxide; SNAP; sodium chloride; sodium nitroprusside; superoxide; tracheal perfusion; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Physiology; klinisk fysiologi;

    Sammanfattning : Inhaled nitric oxide (NO) relaxes smooth muscle of the airways and of pulmonary blood vessels and is used to treat lung diseases where the pulmonary vessels are constricted. NO has also been tested as a bronchodilator in asthmatic patients. LÄS MER

  3. 2. Transcriptome analysis on in vivo derived laser microbeam microdissected cells. Analysis of smooth muscle transcriptomes

    Författare :Stefan Johannes Scheidl; Göteborgs universitet; []
    Nyckelord :microarray; laser microdissection; RNA amplification; smooth muscle cells; smooth muscle differentiation; smooth muscle transcriptome; smooth muscle diversity;

    Sammanfattning : Smooth muscle cells (SMCs) are found in the respiratory, urogenital, circulatory and digestive systems. They provide contractility and structural support for those organs and perform multiple physiological important functions, such as modulation of blood pressure, regulation of airway resistance, and control of gastrointestinal and genitourinary motility. LÄS MER

  4. 3. PACAP and airway regulation with special reference to smooth muscle and neutrophils

    Författare :Johan Kinhult; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; audiology; auditive system and speech; Otorinolaryngologi; audiologi; hörsel- och talorganen; Otorhinolaryngology; allergy; neutrophils; smooth muscle; PACAP; airway regulation;

    Sammanfattning : The investigations focus on the neuropeptidepituitary adenylate cyclase-activating peptide and its effects on airway regulation, with emphasis on smooth muscle relaxation and neutrophil activation and migration. In the nasal mucosa, PACAP-containing nerve fibers were localized invascular smooth muscle and close to seromucous glands. LÄS MER

  5. 4. Platelets and airway remodeling : Mechanisms involved in platelet-induced fibroblast and airway smooth muscle cell proliferation in vitro

    Författare :Ann-Charlotte B. Svensson Holm; Torbjörn Bengtsson; Eva Lindström; Mikael Adner; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Airway remodeling is a contributing cause to the pathological structural changes, such as increased cell proliferation, observed in asthma. Platelets have been found in autopsy lungmaterial obtained from asthmatic patients and are well known to induce proliferation in vitro of a variety of cells. LÄS MER

  7. 5. Cytokine induced airway hyperreactivity characterized in an in-vitro model of asthma

    Författare :Yaping Zhang; Klinisk och experimentell allergiforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicology; Farmakologi; farmakognosi; MAPK; TNF-alpha; 5-HT; Respiratory system; Andningsorganen; Pharmacological sciences; pharmacognosy; pharmacy; interleukin-1beta; hyperresponsiveness; endothelin-1; airway; bradykinin; toxikologi; farmaci;

    Sammanfattning : Asthma is a chronic disorder of the lower airways, characterized by inflammation and hyperreactivity. Pro-inflammatory cytokines like tumour necrosis factor-alpha (TNF-alpha) and interleukin-1beta (IL-1beta) are known to play important roles in the pathogenesis, but our knowledge how these cytokines contribute to the development of airway hyperreactivity is limited. LÄS MER