Sökning: "Neural Progenitor Cell"
Visar resultat 1 - 5 av 135 avhandlingar innehållade orden Neural Progenitor Cell.
1. Novel Regulators of Brain Tumor Development : – From neural stem cell differentiation to in vivo models
Sammanfattning : Malignant brain tumors are diseases with poor prognosis and/or severe long-term side effects of treatment. This thesis aimed to discover novel regulators in brain tumor development, based on studying neural stem cell and progenitor cell (NSPC) differentiation and using animal models to introduce new insights to mechanisms of human brain tumors. LÄS MER
2. Genetic pathways controlling CNS development : The role of Notch signaling in regulating daughter cell proliferation in Drosophila
Sammanfattning : The human central nervous system (CNS) displays the greatest cellular diversity of any organ system, consisting of billions of neurons, of numerous cell sub-types, interconnected in a vast network. Given this enormous complexity, decoding the genetic programs controlling the multistep process of CNS development remains a major challenge. LÄS MER
3. Genetic mechanisms regulating proliferation and cell specification in the Drosophila embryonic CNS
Sammanfattning : The central nervous system (CNS) consists of an enormous number of cells, and large cellular variance, integrated into an elaborate network. The CNS is the most complex animal organ, and therefore its establishment must be controlled by many different genetic programs. LÄS MER
4. Neural stam cells, TLX, and Neuroblastoma
Sammanfattning : Neuroblastoma (NB) is one of the most commonly diagnosed extracranial tumors in children below five years of age. Moreover, NB accounts for almost 12-15% of all childhood cancer related fatalities. To date, the origin of NB has been linked to the neural crest derived sympathoadrenal progenitor cells. LÄS MER
5. Neural Stem and Progenitor Cells : Cellular Responses to Known and Novel Factors
Sammanfattning : Neural stem cell self-renewal and differentiation are tightly regulated events during CNS development, leading to cell division into new neural stem cells or the formation of neurons and glial cells. This thesis focuses on the cellular responses induced by known and novel factors in neural stem and progenitor cells (NSPCs). LÄS MER