Sökning: "synaptophysin"

Visar resultat 1 - 5 av 26 avhandlingar innehållade ordet synaptophysin.

  1. 1. Prostate cancer and neuroendocrine differentiation. Molecular aspects in prostate cancer development

    Författare :Nastaran Monsef; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; neuron specific enolase; neuroendocrine differentiation; serotonin; hypoxia; cancer stem cell; synaptophysin; Gleason score; chromogranin A; Gleason grade;

    Sammanfattning : Hormone refractory prostate cancer occurs when androgen-deprivation therapy (ADT) fails to stop the growth of prostate cancer for any longer. Recent studies point towards a role for neuroendocrine (NE) differentiation in the development of hormone refractory disease. LÄS MER

  3. 2. The Human Spiral Ganglion

    Författare :Sven Tylstedt; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Otorhinolaryngology; human spiral ganglion; ultrastructural morphology; neural interaction; synaptophysin; connexin; membrane specializations; synapse; gap junction; tight junction; Otorhinolaryngologi; Otorhinolaryngology; Otorhinolaryngologi; Oto-Rhino-Laryngology; oto-rhino-laryngologi;

    Sammanfattning : Our knowledge of the fine structure of the Human Spiral Ganglion (HSG) is still inadequate and new treatment techniques for deafness using electric stimulation, call for further information and studies on the neuronal elements of the human cochlea. This thesis presents results of analyses of human cochlear tissue and specimens obtained during neurosurgical transpetrosal removal of life-threatening meningeomas. LÄS MER

  4. 3. Stress steroids as accelerators of Alzheimer's disease. : Effects of chronically elevated levels of allopregnanolone in transgenic AD models

    Författare :Sara Bengtsson; Mingde Wang; Torbjörn Bäckström; Maja Johansson; Caroline Graff; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Allopregnanolone; Alzheimer s disease; beta-amyloid; synaptophysin; chronic stress; Morris water maze; obstetrik och gynekologi; Obstetrics and Gynaecology; medicinsk farmakologi; Medical Pharmacology; Neurology; neurologi; Geriatrics; geriatrik; medical behavioral science; medicinsk beteendevetenskap;

    Sammanfattning : Background Alzheimer’s disease (AD) and dementia are devastating con­ditions not only for the affected patients but also for their families.  The economical costs for the society are tremendous. LÄS MER

  5. 4. New markers for neuroendocrine tumours : with special reference to islet amyloid polypeptide, synaptophysin and chromogranin

    Författare :Mats Stridsberg; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  7. 5. Interactions between neuronal nicotinic acetylcholine receptors, N-methyl-aspartate receptors and beta-amyloid in the brain of genetically modified mice : implications for Alheimer's disease

    Författare :Christina Unger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Abeta; Alzheimer s disease; APP; nAChR; NMDA receptors; synaptophysin; transgenic mice; treatment;

    Sammanfattning : The amyloid hypothesis is one of the leading theories in the search for the cause of Alzheimer's disease (AD) and is based on the theory that hyperproduction and accumulation of amyloid betapeptide (Abeta) in the brain triggers the disruption of neuronal and synaptic function, thereby ultimately leading to neurodegeneration and dementia. Some of the crucial questions are if Abeta has a neuronal function in the brain and how it interacts with the neurotransmitter system in AD. LÄS MER