Sökning: "leukaemia"

Visar resultat 11 - 15 av 112 avhandlingar innehållade ordet leukaemia.

  1. 11. Biological markers in breast cancer and acute leukaemia with focus on drug resistance

    Författare :Elisabet Tina; Ulf Tidefelt; Sten Wingren; Mats G. Karlsson; Jan-Ingvar Jönsson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; acute leukaemia; drug resistance; toposiomerase IIa; BCRP; HER2; SLC25A43; flow cytometry; real time PCR; whole genome screening; MEDICINE; MEDICIN; Oncology; Onkologi; Biomedicin; Biomedicine;

    Sammanfattning : .... LÄS MER

  3. 12. DNA methylation in T cell leukaemia

    Författare :Maike Bensberg; Colm Nestor; Maria Jenmalm; Sofie Degerman; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : T cell acute lymphoblastic leukaemia (T-ALL) is a predominantly paediatric cancer that stems from malignant transformation of developing T cells. While the disease has an overall survival rate of 80%, the intense chemotherapy treatment causes severe toxicity and long-term side effects. LÄS MER

  4. 13. Daily life problems from a nursing perspective in patients with acute leukaemia or highly malignant lymphoma

    Författare :Lena Persson; Institutionen för hälsovetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spouses; family; sense of coherence; quality of life; nursing care; highly malignant lymphoma; acute leukaemia; Physical medicine; kinesitherapy; revalidation; rehabilitation; Rehabilitering medicinsk och social ;

    Sammanfattning : The aims of this thesis were, to investigate the impact on daily living of acute leukaemia or highly malignant lymphoma when under treatment, viewed retrospectively and from a longitudinal perspective, from the point of view of the patients and their spouses, and to ascertain their view of the nursing care provided. A combination of qualitative and quantitative methods was use i. LÄS MER

  5. 14. Regulation of tissue factor expression in myeloid and monocytic leukaemia cells

    Författare :Taavo Tenno; Uppsala universitet; []
    Nyckelord :Medical sciences; tissue factor; blood coagulation; monocytes; cell differentiation; retinoic acid; vitamin D3; acute promyelocytic leukaemia; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Clinical Chemistry; klinisk kemi;

    Sammanfattning : Tissue factor (TF) is a transmembrane glycoprotein that initiates the blood coagulation cascade and is also involved in cell migration, tumour metastasis and angiogenesis. Pathologic expression of tissue factor by monocytes contributes to several thrombotic complications like acute coronary artery disease and disseminated intravascular coagulation. LÄS MER

  7. 15. Studies of leukotriene C4 synthase expression and regulation in chronic myeloid leukaemia

    Författare :Cecilia Roos; Susanne Tornhamre; Anita Sjölander; Karlstads universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; leukotriene C4 synthase; chronic myeloid leukaemia; p210 BCR-ABL; myelopoiesis; imatinib mesylate; Cell biology; Cellbiologi; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : Leukotriene (LT) C4 is generated through conjugation of LTA4 with glutathione by the actions of leukotriene C4 synthase (LTC4S). This biologically potent mediator of asthma and inflammation has also been suggested to play a regulatory role in human myelopoiesis and is overproduced by blood and bone marrow cells from patients with chronic myeloid leukaemia (CML). LÄS MER