Sökning: "Ulf Tidefelt"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden Ulf Tidefelt.
1. Differential-algebraic equations and matrix-valued singular perturbation
Sammanfattning : With the arrival of modern component-based modeling tools for dynamic systems, the differential-algebraic equation form is increasing in popularity as it is general enough to handle the resulting models. However, if uncertainty is allowed in the equations — no matter how small — this thesis stresses that such equations generally become ill-posed. LÄS MER
2. Coagulase-negative staphylococci in hematological malignancy
Sammanfattning : Bacterial infections are common in hematological malignancy. Coagulase-negative staphylococci (CoNS) are among the most prevalent causes of bacteremia in patients with hematological malignancies. LÄS MER
3. Molecular epidemiology of methicillin-resistant staphylococcus aureus : epidemiological aspects of MRSA and the dissemination in the community and in hospitals
Sammanfattning : Methicillin-resistenta Staphylococcus aureus (MRSA) som bär på genen mecA, har förekommit och spridit sig över hela världen, främst i sjukhusmiljö, och orsakat utbrott av vårdrelaterade (så kallade nosokomiala) infektioner. Dessa infektioner kan inte behandlas med stafylokock-penicilliner och MRSA-bakterierna är ofta resistenta även mot flera andra grupper av antibiotika vilket medför att infektionerna ofta är påtagligt svårbehandlade. LÄS MER
4. Biomarkers in non-small cell lung carcinoma : methodological aspects and influence of gender, histology and smoking habits on estrogen receptor and epidermal growth factor family receptor signalling
Sammanfattning : Non-small cell lung carcinoma is a leading cause of cancer mortality worldwide. There are gender and smoking associated differences both in tumour types and clinical outcome. Squamous cell carcinomas (SCC) are more frequent among smoking men while females develop adenocarcinomas (ADCA). LÄS MER
5. On mechanisms of drug resistance in acute myeloid leukemia
Sammanfattning : In this thesis focus has been to increase the knowledge and understanding of some of the mechanisms responsible for drug resistance in acute myeloid leukemia, as well as identify possibilities to predict drug resistance at diagnosis.We have studied the intracellular behavior of cytostatic drugs and their main metabolites (paper I) and the cellular response to cytostatic drugs (paper III). LÄS MER