Sökning: "exocrine function"
Visar resultat 11 - 15 av 26 avhandlingar innehållade orden exocrine function.
11. Developmental and methodological aspects of intestinal and pancreatic function in pigs and rats
Sammanfattning : The gastrointestinal tract has two opposing functions; to effectively absorb nutrients and to act as a safety barrier against hazardous substances in the environment. After birth these functions develops gradually. LÄS MER
12. The Carboxyl Ester Lipase Gene. Organization, Evolution and Transcriptional Regulation in Exocrine Pancreas and Mammary Gland
Sammanfattning : The carboxyl ester lipase (CEL) is an important enzyme for the intestinal absorption of dietary lipids. In humans the gene is highly expressed in exocrine pancreas and in the lactating mammary gland. It is secreted in an inactive form and becomes activated by bile salts in the intestine. LÄS MER
13. Autonomic dysfunction in primary Sjögren's syndrome
Sammanfattning : The aims of this work were to evaluate objective and subjective signs of autonomic dysfunction (AD) in patients with primary Sjögren’s syndrome (pSS) and to evaluate its clinical associations. In study I, 46 pSS patients and 56/80/238 autonomic nervous function test (ANT) controls participated. LÄS MER
14. Enterovirus Implications in Type 1 Diabetes
Sammanfattning : Human enteroviruses (HEVs), particularly Coxsackie B viruses (CVBs), might trigger the onset of type 1 diabetes (T1D), either by direct infection of the insulin-producing beta-cells or by an indirect inflammatory response. The overall aim of this thesis was to study the tropism of HEVs in isolated human pancreatic cell clusters in vitro including virus effects on islet function, gene-expression and ultrastructure. LÄS MER
15. Pancreas Transplantation: Development of Successful Preclinical Models
Sammanfattning : Pancreas transplantation is today a technically successful procedure and provides an alternative to insulin injections for the treatment of Type I diabetes mellitus. This thesis was undertaken while pancreas transplantation was developing and while several fundamental questions were being asked about both endocrine and exocrine drainage of the transplanted pancreas as well as how best to diagnose and prevent rejection. LÄS MER