Sökning: "endoplasmic reticulum"

Visar resultat 16 - 20 av 185 avhandlingar innehållade orden endoplasmic reticulum.

  1. 16. In vivo analysis of amino acid permease folding in yeast

    Författare :Andreas Ring; Per O. Ljungdahl; George Diallinas; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nutrient sensing; signal transduction; endoprotease; subcellular fractionation; membrane-localized chaperone; amino acid permease; endoplasmic reticulum; membrane protein folding; Saccharomyces cerevisiae; Cell Biology; cellbiologi;

    Sammanfattning : Plasma membrane (PM) proteins are critical for cells to respond to environmental cues, such as the availability of nutrients. The yeast Saccharomyces cerevisiae is able to sense extracellular amino acids using the SPS sensing system. LÄS MER

  3. 17. Investigation of Neuronal Protein Trafficking at the Molecular Scale

    Författare :Martina Damenti; Ilaria Testa; Clive Bramham; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Endoplasmic Reticulum; Mitochondria; Arc Activity-regulated cytoskeleton-associated protein ; oligomerization; pRESOLFT; STED; event-triggered FCS; DNA-PAINT; STARSS; molecular dynamics simulations; Biological and Biomedical Physics; Biologisk och biomedicinsk fysik;

    Sammanfattning : Neurons are polarized cells that encode information in the nervous system viaelectrochemical connections named synapses. The tuning of synapticconnections is enabled by a plastic protein trafficking system which operates atthe nanoscale to finely tweak the neuronal ultrastructure. LÄS MER

  4. 18. Fatty Acyl Reductases and Fatty Acyl Desaturases. Deciphering the biosynthesis of species-specific moth female sex pheromones from common fatty acids

    Författare :Åsa Hagström; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Moth; pheromone; insect; evolution; fatty acyl desaturase; fatty acyl reductase; endoplasmic reticulum; fatty acid biosynthesis; GFP; heterologous expression; phylogeny; cell factory; lepidoptera;

    Sammanfattning : Moths (Lepidoptera) are dependent on female produced pheromones, chemical signals, for attracting a mate. Pheromones are most commonly made up by saturated and/or unsaturated fatty acid derived alcohols, acetates, and/or aldehydes that are produced by a set of enzymes in the female pheromone gland. LÄS MER

  5. 19. Pulling Force Studies of Secretory Protein Translocation into the Endoplasmic Reticulum

    Författare :Theresa Kriegler; Tara Hessa; Patricia Clark; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Co-translational translocation; Xbp1 arrest peptide; Translocon-associated protein TRAP complex; Prion protein; Insulin; Biochemistry; biokemi;

    Sammanfattning : More than 30% of human genes encode secretory or membrane proteins. Most secretory proteins are targeted to the Endoplasmic reticulum (ER) membrane via cleavable N-terminal signal sequences either in a co- or post-translational manner. They enter or cross the membrane using a protein translocating channel (translocon). LÄS MER

  7. 20. Mitochondria-endoplasmic reticulum contacts in neuronal cells : from physiology to therapeutics

    Författare :Giacomo Dentoni; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mitochondria and the endoplasmic reticulum (ER) are intracellular organelles that play vital physiological functions. Mitochondria are key players in energy production through adenosine triphosphate (ATP) production and calcium (Ca2+) buffering, while the ER is involved in protein and lipid synthesis along with Ca2+ signalling in the cell. LÄS MER