Sökning: "electrospray ionization mass spectrometry"
Visar resultat 6 - 10 av 81 avhandlingar innehållade orden electrospray ionization mass spectrometry.
6. Electrophoretic focusing in microchannels combined with mass spectrometry : Applications on amyloid beta peptides
Sammanfattning : Analysis of low-abundance components in small samples remains a challenge within bioanalytical chemistry, and new techniques for sample pretreatments followed by sensitive and informative detection are required. In this thesis, procedures for preconcentration and separation of proteins and peptides in open microchannels fabricated on silicon microchips are presented. LÄS MER
7. New Materials and Improved Ambient Techniques in Mass Spectrometry
Sammanfattning : Mass spectrometry (MS) is used in several fields, e.g. biology, environmental monitoring, medicine and forensics due to excellent qualitative and quantitative capabilities. The development of new instrumental setups and ionization sources is crucial to analyze a variety of compounds at trace levels. LÄS MER
8. Metabolic Studies with Liquid Separation Coupled to Mass Spectrometry
Sammanfattning : Metabolism is the sum of all chemical processes with the purpose to maintain life, as well as enable reproduction, in a living organism. Through the study of metabolism, increased understanding of pharmacological mechanisms and diseases can be achieved. LÄS MER
9. Electrospray Ionization Mass Spectrometry for Determination of Noncovalent Interactions in Drug Discovery
Sammanfattning : Noncovalent interactions are involved in many biological processes in which biomolecules bind specifically and reversibly to a partner. Often, proteins do not have a biological activity without the presence of a partner, a ligand. LÄS MER
10. Aspects of Porous Graphitic Carbon as Packing Material in Capillary Liquid Chromatography
Sammanfattning : In this thesis, porous graphitic carbon (PGC) has been used as packing material in packed capillary liquid chromatography. The unique chromatographic properties of PGC has been studied in some detail and applied to different analytical challenges using both electrospray ionization-mass spectrometry (ESI-MS) and ultra violet (UV) absorbance detection. LÄS MER