Sökning: "context-dependent signaling"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden context-dependent signaling.

  1. 1. Application of Proximity Ligation Assay for Multidirectional Studies on Transforming Growth Factor-β Pathway

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Agata Zieba; Uppsala universitet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; proximity ligation; TGF-β signaling; Smad; single cell analysis; cell cycle; context-dependent signaling; CRC; Molekylär cellbiologi; Molecular Cellbiology; Medicinal Chemistry; Läkemedelskemi; Molecular Biology; Molekylärbiologi;

    Sammanfattning : A comprehensive understanding of how the body and all its components function is essential when this knowledge is exploited for medical purposes. The achievements in biological and medical research during last decades has provided us with the complete human genome and identified signaling pathways that governs the cellular processes that facilitates the development and maintenance of higher order organisms. LÄS MER

  2. 2. Wnt5a signaling in Malignant Melanoma

    Detta är en avhandling från Department of Laboratory Medicine, Lund University

    Författare :Elin Ekström; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The Wnt signaling pathway is highly conserved and crucial during embryonic development. Aberrant Wnt signaling is important in several different disease processes. One such disease process is the development and progression of cancer. Malignant melanoma is a highly aggressive tumor type, in which Wnt signaling is essential. LÄS MER

  3. 3. Thymic Stroma and T Cell Development. Impacts of Retinoic Acid Signaling

    Detta är en avhandling från Lund University, Faculty of Medicine

    Författare :Kerstin Wendland; Lunds universitet.; Lund University.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Thymus; Thymic epithelial cells; Retinoic acid; T cell development; Stromal Cells;

    Sammanfattning : The development of functionally competent, self-tolerant T cells in the thymus is an essential prerequisite for the formation of adaptive immune responses against foreign pathogens. Thymic epithelial cells (TECs) form specialized stromal microenvironments in the cortex (cTEC) and medulla (mTEC) of the thymus that support all stages of T cell development, from the entry of thymocyte progenitors to the exit of mature naive T cells. LÄS MER

  4. 4. Genetic pathways controlling CNS development The role of Notch signaling in regulating daughter cell proliferation in Drosophila

    Detta är en avhandling från Linköping : Linköping University Electronic Press

    Författare :Caroline Bivik Stadler; Linköpings universitet.; Linköpings universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : The human central nervous system (CNS) displays the greatest cellular diversity of any organ system, consisting of billions of neurons, of numerous cell sub-types, interconnected in a vast network. Given this enormous complexity, decoding the genetic programs controlling the multistep process of CNS development remains a major challenge. LÄS MER

  5. 5. Context-addressed communication dispatch

    Detta är en avhandling från Stockholm : KTH

    Författare :Alisa Devlic; KTH.; [2009]
    Nyckelord :Context-addressed messaging; Context-aware session control; Context-aware communication; Context-aware call signaling; Context-based session initiation;

    Sammanfattning : This research concerns exploiting knowledge of the user's environment (i.e. LÄS MER