Sökning: "Retinoic acid"
Visar resultat 1 - 5 av 128 avhandlingar innehållade orden Retinoic acid.
1. Effects of retinoic acid in the mouse olfactory sensory systems
Sammanfattning : A common characteristic in neurodegenerative diseases of the brain is death of specific neuronal populations. The lack of neuron proliferation and axon extension in most parts of the central nervous system leads to chronic loss of neurons in the case of injury or disease. LÄS MER
2. Thymic Stroma and T Cell Development. Impacts of Retinoic Acid Signaling
Sammanfattning : The development of functionally competent, self-tolerant T cells in the thymus is an essential prerequisite for the formation of adaptive immune responses against foreign pathogens. Thymic epithelial cells (TECs) form specialized stromal microenvironments in the cortex (cTEC) and medulla (mTEC) of the thymus that support all stages of T cell development, from the entry of thymocyte progenitors to the exit of mature naive T cells. LÄS MER
3. CYP26B1 as regulator of retinoic acid in vascular cells and atherosclerotic lesions
Sammanfattning : Cardiovascular disease (CVD), currently the most common cause of morbidity and mortality worldwide, is caused mainly by atherosclerosis. Atherosclerosis is a chronic multifocal, immunoinflammatory, fibroproliferative disease of medium and large arteries. LÄS MER
4. Retinoic Acid Metabolism Blocking Agents and the Skin : In vivo and in vitro Studies of the Effects on Normal and Diseased Human Epidermis
Sammanfattning : Retinoic Acid Metabolism Blocking Agents (RAMBAs) increase the endogenous levels of all-trans retinoic acid (RA) by inhibiting CYP26 enzymes. Thus they are believed to mimic the effects of retinoid treatment. Their mechanism of action and effects on vitamin A metabolism in keratinocytes are however uncertain. LÄS MER
5. Effects of ellagic acid in human neuroblastoma cells
Sammanfattning : A diet rich in polyphenols has been proposed to have beneficial health effects and to reduce risk of disease. Ellagic acid, a polyphenol common in red berries and pomegranates, has potential anti-tumorigenic effects that make it interesting to further study in different cancer cell systems. LÄS MER