Sökning: "context-dependent signaling"

Visar resultat 6 - 10 av 13 avhandlingar innehållade orden context-dependent signaling.

  1. 6. Context-addressed communication dispatch

    Författare :Alisa Devlic; Gerald Maguire; Rasmus Rasmus Løvenstein Olsen; KTH; []
    Nyckelord :Context-addressed messaging; Context-aware session control; Context-aware communication; Context-aware call signaling; Context-based session initiation;

    Sammanfattning : This research concerns exploiting knowledge of the user's environment (i.e. LÄS MER

  3. 7. Exploring the potential of antiangiogenic strategies targeting the TGF-β family in the tumor microenvironment

    Författare :Sara Cunha; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Members of the transforming growth factor (TGF)-β family exert their effect on virtually all cell types in the body, producing diverse and complex cellular responses. Additionally, TGF-β signaling is deregulated and hyperactive in many malignant conditions, making it an appealing target in the combat of cancer disease. LÄS MER

  4. 8. Notch in cancer and cancer metabolism : six degrees of intracellular turbulence

    Författare :Sebastian K-J Landor; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Notch signaling is an evolutionarily conserved cell-to-cell contact-dependent signaling mechanism in multicellular organisms directing cellular fates both in early development and adult tissues. In metazoans the Notch pathway consists of multiple paralogs of receptors and ligands constituting a complex juxtacrine communications network orchestrating organismal homeostasis. LÄS MER

  5. 9. Molecular mechanisms underlying the actions of psychoactive drugs in the basal ganglia : focus on cannabinoids and morphine

    Författare :Anders Borgkvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis is centered on the identification of the molecular mechanisms involved in the psychomotor effects of cannabinoids and morphine. These drugs share the ability of acting at the level of the basal ganglia, a group of subcortical structures involved in the control of locomotion, as well as in cognitive and motivational aspects of motor function. LÄS MER

  7. 10. On molecular mechanisms of neural differentiation and forebrain development

    Författare :Erik Södersten; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Telencephalic development is an extraordinary complex process where neural structures of highly diverse cell compositions emerge as the result of multiple developmental strategies imposing tight regulation, balance and timing of gene expression. Embryonic telencephalic neural stem cells (NSCs) can form the major cell types found in the telencephalon, and are thus an excellent model for studying transcriptional control of lineage choice mechanisms in CNS development. LÄS MER