Sökning: "complex repeats"

Visar resultat 1 - 5 av 49 avhandlingar innehållade orden complex repeats.

  1. 1. Telomeric DNA in Chironomus, a naturally telomerase-free system

    Författare :Monika Rosén; Udo Häckers grupp Utvecklingsbiologi i invertebrater; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology; Chironomus; extrachromosomal telomeric repeats; RNA-DNA complex; 3´overhang; telocentric chromosome end; Telomere; complex repeats; Biologi; Genetics; cytogenetics; Genetik; cytogenetik;

    Sammanfattning : Telomeres are specialized complexes of DNA and associated proteins that protect the ends of eukaryotic chromosomes. Although most organisms have short repeated DNA sequences at their telomeres, which are specified and maintained by the enzyme telomerase, there are a few exceptions. LÄS MER

  3. 2. Classes of DNA associated with telomeres in the chironomids C. pallidivittatus and C. tentans

    Författare :Iréne Kamnert; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genetics; Chironomus; subtelomere; gene conversion; subfamilies; telomere; complex repeats; cytogenetics; Genetik; cytogenetik;

    Sammanfattning : Telomeres in Chironomus consist of long complex tandem DNA repeats, which in C. pallidivittatus have been shown to extend to the extreme end of chromosomes. In C. pallidivittatus the telomeric repeats are present in large blocks, 50-200kb in size, most of them belonging to four major subfamilies. LÄS MER

  4. 3. Development of benzoquinoquinoxaline derivatives as triplex-specific probes : Recognition of DNA structures at repeats sequences

    Författare :Helen Bergquist; Rula Zain; Keith Fox; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Triplex; H-DNA; BQQ; BQQ-OP; BQQ-Bodipy; triplet repeat; DNA; non-B-DNA; pkd1; frataxin; Friedreich s ataxia; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Sammanfattning : Repeat sequences are associated with several human diseases, such as Friedreich’s ataxia, polycystic kidney disease and cancer. These sequences can form non-B-DNA structures, including triplex (H-DNA) DNA, and are associated with genomic instability and altered gene expression. LÄS MER

  5. 4. Structural Studies of Flexible Biomolecules and a DNA-binding Protein

    Författare :Tariq Massad; Pål Stenmark; Cheryl Arrowsmith; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Maximum entropy; motilin; DNA-binding proteins; Karplus equation; disaccaride; direct repeats; Structural biology; Strukturbiologi; Biophysics; biofysik;

    Sammanfattning : The knowledge of the three-dimensional structures of proteins and polypeptides is essential to understand their functions. The work shown in this thesis has two objectives. LÄS MER

  7. 5. Regulation of the Epstein-Barr virus C promoter by the OriP-EBNA1 complex

    Författare :Cecilia Boreström; Göteborgs universitet; []
    Nyckelord :Epstein-Barr virus; EBNA1; NF-Y; Sp1; Oct-2; Bright; E2F1; transcriptional regulation; Cp; oriP;

    Sammanfattning : Epstein-Barr Virus (EBV) is an exclusively human, lymphotropic herpes virus that infects more than 90% of the population worldwide. Primary infection usually occurs during the early years of life and does not result in any recognized disease. LÄS MER