Sökning: "E2F1"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet E2F1.

  1. 1. Regulation of the Epstein-Barr virus C promoter by the OriP-EBNA1 complex

    Författare :Cecilia Boreström; Göteborgs universitet; []
    Nyckelord :Epstein-Barr virus; EBNA1; NF-Y; Sp1; Oct-2; Bright; E2F1; transcriptional regulation; Cp; oriP;

    Sammanfattning : Epstein-Barr Virus (EBV) is an exclusively human, lymphotropic herpes virus that infects more than 90% of the population worldwide. Primary infection usually occurs during the early years of life and does not result in any recognized disease. LÄS MER

  3. 2. Antiproliferative action of estrogen receptor beta and Hes-1 in breast cancer

    Författare :Johan Hartman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Breast cancer is the most common malignancy among Swedish women. Although the mechanism behind the tumorigenesis remains unclear, estrogen receptor a (ERa) plays an important role in the progression of breast cancer and is regarded as a target for endocrine therapy. LÄS MER

  4. 3. Role of mitochondrial ribosomal protein S18-2 in cancerogenesis and in regulation of stemness and differentiation

    Författare :Muhammad Mushtaq; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mitochondria carry their own ribosomes (mitoribosomes) for the translation of mRNA encoded by mitochondrial DNA. The architecture of mitoribosomes is mainly composed of mitochondrial ribosomal proteins (MRPs), which are encoded by nuclear genomic DNA. LÄS MER

  5. 4. Understanding the role of regulatory RNAs in human skin wound healing

    Författare :Letian Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Human skin wound healing is characterized by four phases in a timely manner, including hemostasis, inflammation, proliferation, and remodeling. Various cell types are involved in the biological process. LÄS MER

  7. 5. The Epstein-Barr nuclear antigens 1 & 5; Study of virus-host cellular protein interactions

    Författare :Alma Forsman; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Epstein-Barr virus; EBNA1; EBNA5; EBNA-LP; cellular network; virus-host protein interactions;

    Sammanfattning : The Epstein-Barr virus (EBV) is the causative agent or cofactor in the aetiology of several human malignancies such as Burkitt’s lymphoma, Hodgkin’s disease, nasopharyngeal carcinoma (NPC) and lymphoproliferative disorder in immunocompromised patients. EBV is a lymphotropic γ-herpes virus infecting more than 90 percent of the population worldwide. LÄS MER