Sökning: "cell-cell"

Visar resultat 11 - 15 av 166 avhandlingar innehållade ordet cell-cell.

  1. 11. Regulation of the cytoskeleton and the adhesiveness of intestinal epithelial cells by leukotriene D4

    Författare :Ramin Massoumi; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; PKC; vinculin; actin filament; focal adhesion; LTD4; integrin; cancerology; Cytologi; onkologi; cancer; Biochemistry; Metabolism; Biokemi; metabolism;

    Sammanfattning : Leukotrienes belong to a family of biologically active conjugated trienes that are formed from arachidonic acid via the 5-lipoxygenase pathway and are important mediators of inflammatory reactions. The CysLT1 receptor that specifically serves as receptor for leukotriene D4 (LTD4) has been identified as a G-protein coupled receptor. LÄS MER

  2. 12. Regulation of Type I Interferon Production in Plasmacytoid Dendritic Cells : Effect of Genetic Factors and Interactions with NK Cells and B Cells

    Författare :Olof Berggren; Maija-Leena Eloranta; Niels Heegaard; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Systemic lupus erythemtosus; IFN-alpha; autoimmunity; immune complex; single nuclear polymorphisms; Medicinsk vetenskap; Medical Science;

    Sammanfattning : The type I interferon (IFN) system plays a central role in the etiopathogenesis of many autoimmune diseases, e.g. systemic lupus erythematosus (SLE). Activation of the type I IFN system in SLE is promoted by endogenous nucleic acid-containing immune complexes (ICs) which stimulate plasmacytoid dendritic cells (pDCs). LÄS MER

  3. 13. Feeling the force : role of AmotL2 in normal development and cancer

    Författare :Aravindh Subramani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cells that fabricate the body, dwell in a very heterogeneous environment. Self-organization of individual cells into complex tissues and organs at the time of growth and revival is brought about by the combinatory action of biomechanical and biochemical signaling processes. LÄS MER

  4. 14. Molecular factors influencing epithelial-mesenchymal transition in breast cancer

    Författare :Gisela M A Nilsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; breast cancer; epithelial-mesenchymal transition; c-erbB2; E-cadherin; NFI-C2; FoxF1; LOX;

    Sammanfattning : Epithelial-mesenchymal transition (EMT) is a developmental process defined by loss of epithelial characteristics and acquisition of mesenchymal phenotype. EMT or similar processes are also implicated in carcinoma cell invasion and the progression of breast carcinoma to metastasis. LÄS MER

  5. 15. Creating cell microenvironments in vitro

    Författare :Patric Wallin; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cell migration; lipid bilayers; cell differentiation; liquid handling; surface functionalization; Microfluidics; chemotractant gradients; mammalian cell culture; cell microenvironments; in vitro screening assay;

    Sammanfattning : Stem cells have a great potential to bring about advancements in fields like developmental biology, drug discovery, cancer biology and tissue engineering. In order to be able to use stem cells to their full potential, it is important to have control over their behavior. LÄS MER