Sökning: "Lars Wallentin"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden Lars Wallentin.

1. 1. On the Prediction of Warfarin Dose

   Författare :Niclas Eriksson; Mia Wadelius; Lars Wallentin; Lars Berglund; Patrik Magnusson; Uppsala universitet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Warfarin; pharmacogenetics; prediction models; Dosing algorithm; GWAS; VKORC1; CYP2C9; Clinical Pharmacology; Klinisk farmakologi;

   Sammanfattning : Warfarin is one of the most widely used anticoagulants in the world. Treatment is complicated by a large inter-individual variation in the dose needed to reach adequate levels of anticoagulation i.e. INR 2. LÄS MER

3. 2. Development and use of a modular prototype system

   Författare :Lars Wallentin; KTH; []
   Nyckelord :;

   Sammanfattning : .... LÄS MER

4. 3. Biomarkers of inflammation in atrial fibrillation

   Författare :Julia Aulin; Jonas Oldgren; Ziad Hijazi; Lars Wallentin; Håkan Wallén; Uppsala universitet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Atrial fibrillation; biomarkers; inflammation; inflammatory biomarkers; oral anticoagulation; heart failure; left ventricular function; ejection fraction; risk assessment; risk prediction; interleukin 6 IL-6 ; C-reactive protein CRP ;

   Sammanfattning : Atrial fibrillation (AF) is common and associated with increased risk of stroke, heart failure (HF) and mortality. Inflammation is linked to AF.The overall aim of this thesis was to investigate inflammatory activity and cardiovascular outcomes and mortality in patients with AF on effective oral anticoagulation. LÄS MER

5. 4. Early Risk Stratification, Treatment and Outcome in ST-elevation Myocardial Infarction

   Författare :Erik Björklund; Bertil Lindahl; Lars Wallentin; Ulf Näslund; Uppsala universitet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Acute myocardial infarction; Thrombolysis; Troponin; Electrocardiography; Natriuretic peptide; Prognosis; Prehospital thrombolysis; Treatment delay; Mortality; Registry; Clinical trial; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

   Sammanfattning : We evaluated, in patients with ST-elevation myocardial infarction (STEMI) treated with thrombolytics, admission Troponin T (tnT), ST-segment resolution and admission N-terminal pro-brain natriuretic peptide (NT-proBNP) for early risk stratification as well as time delays and outcome in real life patients according to prehospital or in-hospital thrombolytic treatment. Also, baseline characteristics, treatments and outcome in patients enrolled in the ASSENT-2 trial in Sweden and in patients not enrolled were evaluated. LÄS MER

7. 5. Regulation of Tissue Factor and Coagulation Activity : Translation Studies with Focus on Platelet-Monocyte Aggregates and Patients with Acute Coronary Syndrome

   Författare :Christina Christersson; Agneta Siegbahn; Lars Wallentin; Jonas Oldgren; Ingebjorg Seljeflot; Uppsala universitet; []
   Nyckelord :Internal medicine; Myocardial infarction; Coagulation; Platelet-monocyte aggregates; Tissue factor; Thrombin inhibition; Invärtesmedicin;

   Sammanfattning : Myocardial infarction (MI) is often caused by a disruption of an atherosclerotic plaque with activation of coagulation, platelets and inflammation. The aims were; to investigate whether the oral direct thrombin inhibitor, ximelagatran affected markers for coagulation, platelet and inflammation in a patient cohort with recent MI and if the coagulation markers could identify patients with increased risk of new ischemic events; to evaluate some of the mechanisms involved in formation of platelet-monocyte aggregates (PMAs). LÄS MER