Sökning: "UPLC"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet UPLC.

1. 1. Analysis of Metabolites in Complex Biological Samples Using LC/MS and Multivariate Data Analysis : Metabolic Fingerprinting and Detection of Biomarkers

   Författare :Helena Idborg; Sven Jacobsson; Per-Olof Edlund; Jonas Bergquist; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metabolomics; Metabonomics; Metabolic Fingerprinting; Drug Metabolism; Biomarkers; Human Plasma; Rat Urine; LC MS; ZIC-HILIC; UPLC; UHPLC; ToF; Curve Resolution; Peak Detection; Pattern Recognition; Classification; PCA; PLS; PARAFAC; N-PLS; Data Fusion; Hierarchical Modeling; Batch modeling; Data Concatenation; Breast Cancer; Phospholipidosis; Analytical chemistry; Analytisk kemi; Analytical Chemistry; analytisk kemi;

   Sammanfattning : To facilitate early diagnosis of diseases and elucidation of the processes involved in their development and progression, various specific compounds or ‘biomarkers’ are often monitored. The first step is to decide which compounds to analyze. LÄS MER

3. 2. Methodologies to assess the fate of polar organic compounds in aquatic environments

   Författare :Jörgen Magnér; Tomas Alsberg; Dag Broman; Jan-Åke Jönsson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Passive equilibrium sampler; Absorbent; Polar organic compounds; Liquid chromatography-mass spectrometry; Partitioning coefficient; Fulvic acid; Sediment; PEVAC; Bag-SPE; Solid phase extraction; Pharmaceuticals; Wastewater; Sea water; UPLC-QToF; Environmental chemistry; Miljökemi; Analytical chemistry; Analytisk kemi; Applied Environmental Science; tillämpad miljövetenskap;

   Sammanfattning : Polar organic compounds (POCs) are chemicals with polar functional groups in their structure. The functional groups make the compounds hydrophilic and less prone to partition with biota. However, the knowledge of their fate is limited due to difficulties associated with their measurements. LÄS MER

4. 3. Occupational exposure to fluorinated ski wax

   Författare :Helena Nilsson; Jonathan W. Martin; Örebro universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Perfluorinated; polyfluorinated; FIS; occupational exposure; ski wax; biotransformation; metabolism; fluorotelomer alcohol; fluorotelomer acid; aerosol; dust; UPLC MS-MS; GC MS-MS; Kemi; Chemistry;

   Sammanfattning : Per- and polyfluorinated substances (PFAS) are used in the production of ski wax to reduce the friction between the snow and the ski. In this occupational study of ski wax technicians’ exposure to PFAS and particulate aerosol we have collected whole blood (wb) (n =94), air (n =84) and aerosol (n =159) samples at World Cup events from 2007-2011. LÄS MER

5. 4. Individualized treatment and control of bacterial infections

   Författare :Hanna Woksepp; Thomas Schön; Anders Johansson; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; therapeutic drug monitoring; intensive care unit; β-lactam antibiotics; antimicrobial drug resistance; molecular typing; whole-genome sequencing; Biomedical Sciences; Biomedicinsk vetenskap;

   Sammanfattning : Infectious diseases cause substantial morbidity and mortality, exacerbated by increasing antibiotic resistance. In critically ill patients, recent studies indicate a substantial variability in β-lactam antibiotic levels when standardized dosing is applied. LÄS MER

7. 5. Determination of folate for food composition data : development and improvement of analytical methods

   Författare :Hanna Sara Strandler; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

   Sammanfattning : Folate is B vitamin that is required for maintaining normal blood status. Recommendations on daily intake are based on information on blood folate status in relation to folate intake and bioavailability. Folate intake from a diet is evaluated by folate content in the food consumed. LÄS MER