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Visar resultat 1 - 5 av 11 avhandlingar som matchar ovanstående sökkriterier.
1. Intrinsically Proton-Conducting Benzimidazole Units Tethered to Different Polymer Chain Architectures
Sammanfattning : Proton transport is a fundamental process that can be found in many systems in nature, as well as in technical devices, such as fuel cells, electrochromic devices and various types of sensors. Fuel cell technology is considered as environmentally friendly because fuel cells are not limited by the Carnot cycle, and efficiently converts chemical energy into electrical energy which can be used for powering cars, laptops, buildings etc. LÄS MER
2. Novel glycomimetic inhibitors and proteolysis-targeting chimeras for human galectins
Sammanfattning : Galectins are a family of soluble proteins that bind β-D-galactopyranoside-containing glycoconjugates through their conserved carbohydrate-recognition domains. Galectins have emerged as promising drug targets due to their involvement in various pathological conditions, such as tumor growth and metastasis, autoimmune and inflammatory diseases, as well as metabolic disorders. LÄS MER
3. Synthesis of sulfur and selenium heterocycles, including derivatives of imidazopyridine and benzimidazole
Sammanfattning : The chemistry developed in this thesis can be divided into two parts. The first part, which is the major part of the thesis, contains syntheses towards analogues to mutagenic heterocyclic amines found in e.g. meat fried at high temperatures. LÄS MER
4. The genetic basis and monitoring of anthelmintic resistance in the pathogenic endoparasites of small ruminants
Sammanfattning : By parasitizing livestock, gastrointestinal nematodes inflict a significant monetaryburden on the producers and compromise animal health as well as the sustainabilityof animal farming systems. To date, the most reliable way to control parasiticinfections in grazing livestock is through the use of anthelmintic drugs. LÄS MER
5. From field to genetics : anthelmintic resistance in the equine roundworm Parascaris univalens
Sammanfattning : The equine roundworm Parascaris univalens is a common parasite of foals. Most foals show mild clinical symptoms, but large worm burdens can lead to severe colic and even death. Regular treatment with anthelmintic drugs has resulted in resistance development, mainly to ivermectin but also to pyrantel and fenbendazole in sporadic cases. LÄS MER