Sökning: "PROTAC"

Hittade 1 avhandling innehållade ordet PROTAC.

1. 1. Novel glycomimetic inhibitors and proteolysis-targeting chimeras for human galectins

   Författare :Mujtaba Hassan; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Galectins; Galectin-3; Galectin-8; benzimidazole; affinity; selectivity; X-ray; PROTAC;

   Sammanfattning : Galectins are a family of soluble proteins that bind β-D-galactopyranoside-containing glycoconjugates through their conserved carbohydrate-recognition domains. Galectins have emerged as promising drug targets due to their involvement in various pathological conditions, such as tumor growth and metastasis, autoimmune and inflammatory diseases, as well as metabolic disorders. LÄS MER