Sökning: "rheumatic antibodies"

Visar resultat 1 - 5 av 36 avhandlingar innehållade orden rheumatic antibodies.

  1. 1. Diabetes mellitus in Adults - Aspects of Incidence, Autoimmunity and C-peptide

    Författare :Maria Thunander; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 diabetes; type 2 diabetes; incidence; epidemiology; c-peptide; classification; antibodies; LADA; insulin; definition; autoimmune diseases; rheumatic antibodies; gastric antibodies; complications;

    Sammanfattning : Type 1 and type 2 diabetes increase worldwide, leading to a heavy burden of disease and its complications. All 1666 adults aged 18-100 years with new onset diabetes in Kronoberg during 3 years were registered, and type of diabetes classified by pancreatic autoantibodies and C-peptide. LÄS MER

  3. 2. Immune Complex Regulated Cytokine Production in Rheumatic and Lymphoproliferative Diseases

    Författare :Linda Mathsson; Johan Rönnelid; Bo Nilsson; Ann Kari Lefvert; Uppsala universitet; []
    Nyckelord :Immunology; Immune complex; Cytokines; Rheumatic diseases; Lymphoproliferative diseases; Immunologi;

    Sammanfattning : Immune complexes (ICs) are produced during normal immune responses and facilitate clearance of foreign antigens. ICs not efficiently cleared from the circulation can cause tissue damage. This might happen if ICs are formed with autoantibodies and autoantigens. LÄS MER

  4. 3. Understanding inflammatory mechanisms in rheumatic diseases

    Författare :Ia Khmaladze; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Rheumatoid arthritis (RA), Psoriasis (Ps) and Psoriasis arthritis (PsA) are chronic inflammatory autoimmune disorders, where primary targets are peripheral joints, skin and skin/joints respectively. Both innate and adaptive immunity play a role in disease initiation and progression. LÄS MER

  5. 4. Pneumococcal vaccination in inflammatory rheumatic disease and in splenectomy patients. From antibody response to memory cells

    Författare :Per Nived; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pneumokockvaccin; konjugerat; Pneumokockpolysackaridvaccin; Inflammatorisk reumatisk sjukdom; Antikroppssvar; Minnesceller; Splenektomi; Pneumococcal conjugate vaccine; Pneumococcal polysaccharide vaccine; rheumatic diseases; antibody response; Splenectomy; memory cells;

    Sammanfattning : Objectives:The overall aim of the dissertation is to examine antibody response to immunization with pneumococcal vaccine in patients with inflammatory rheumatic disease (IRD), in relation to disease-modifying antirheumatic drug (DMARD) treatments, and in postsplenectomy patients.Methods:(I) Splenectomized patients without previous pneumococcal conjugate vaccine (PCV) immunization were invited to receive one dose 13-valent PCV (PCV13). LÄS MER

  7. 5. Reactivity to collagen type II and C1q in rheumatic diseases

    Författare :Johan Rönnelid; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :rheumatoid arthritis; systemic lupus erythematosus; anti-collagen antibodies; anti-Clq antibodies; ELISPOT; interferon-y; IL-4;

    Sammanfattning : In rheumatoid arthritis (RA),other arthritides and in systemic lupus erythematosus (SLE) there is immunological reactivity to collagen type II (CII) and to complement component C1q. Parts of the CII and C1q molecules are structurally and immunologically related. LÄS MER