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Visar resultat 1 - 5 av 92 avhandlingar som matchar ovanstående sökkriterier.
1. The inflammatory response to arterial injury
Sammanfattning : Atherosclerosis as a disease is postulated to stem from a response to injury of the arterial wall by various stimuli. The inflammatory response is proposed to mediate intimal formation after injury. One pathway of cellular response to injury is through transcription factor NF-kB. LÄS MER
2. Injury-Induced Signalling in Arterial Smooth Muscle Cells
Sammanfattning : The vascular wall is an active, elastic and integrated organ made up of cellular and extracellular matrix (ECM) components. It is not a static organ; the components dynamically change and reorganize in response to physiological and pathological stimuli. Vascular injury induces a complex healing process, analogous to generalised wound healing. LÄS MER
3. Clinical Aspects of Pediatric Head Injury
Sammanfattning : Traumatic head injury is one of the leading causes to severe morbidity and death among children. Specific and national management guidelines for pediatric head injuries are lacking in Sweden, and management routines are consequently based on adult guidelines or local guidelines. LÄS MER
4. Intracranial Pressure in Traumatic Brain Injury
Sammanfattning : Traumatic Brain Injury (TBI) continues to be a major problem worldwide. Today, intensive care of patients with TBI is mainely focused on preventing and treating secondary brain injuries. High pressure inside the intracranial cavity (ICP) has been found to be an important feature of disturbed cerebral dynamics and secondary injuries. LÄS MER
5. Antithrombotic Effects of Activated Protein C and Heparins in Deep Arterial Injury
Sammanfattning : The investigations presented in this thesis have evaluated different strategies to prevent thrombosis in an experimental model of deep arterial injury in rats. Unfractionated heparin (UFH) is often used to prevent thrombosis in microvascular surgery and in other vascular interventions, but a major drawback of UFH is increased bleeding. LÄS MER