Sökning: "heparin"

Visar resultat 1 - 5 av 237 avhandlingar innehållade ordet heparin.

1. 1. Interactions between staphylococci, heparin, heparin dependent growth factors and biomaterials

   Författare :Corina Fallgren; Avdelningen för medicinsk mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; and biomaterials bonded with antibiotics; heparin-binding growth factors; staphylococci; heparin; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

   Sammanfattning : Resident skin micro-organisms such as S. epidermidis and other coagulase-negative staphylococci (CoNS), are by far the most common causes of biomaterial-associated infections. These micro-organisms often exhibit surface adhesins that specifically bind serum and tissue proteins adsorbed to implanted biomaterials. LÄS MER

3. 2. Lipoprotein lipase in hemodialysis patients and healthy controls : effects of heparin

   Författare :Birgit Näsström; Per-Ola Attman; Umeå universitet; []
   Nyckelord :dalteparin; dialysis; lipoprotein metabolism; LMWH; LPL; triglycerides; UFH; uremia; medicinsk och fysiologisk kemi; Medical and Physiological Chemistry;

   Sammanfattning : Mortality from cardiovascular disease in patients on chronic hemodialysis (HD) is 10 to 20 times greater than in the general population. One major risk factor is renal dyslipidemia, characterised by an impaired catabolism of triglyceride (TG)-rich lipoproteins with accumulation of atherogenic remnant particles. LÄS MER

4. 3. Heparin coating and cardiotomy suction in cardiopulmonary bypass

   Författare :Staffan Svenmarker; Torkel Åberg; Gunnar Engström; Thomas Karlsson; Jarle Vaage; Umeå universitet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; cardiopulmonary bypass; oxygenators; heparin; S100 proteins; blood loss; haemostasis; memory; outcome and process assessment; Kirurgi; Surgery; Kirurgi; kirurgi; Surgery;

   Sammanfattning : The present thesis addresses various means of reducing inflammatory responses associated with cardiopulmonary bypass (CPB) and retransfusion of pericardial suction blood (PSB) during cardiac surgery. Four (I-IV) prospective randomised controlled clinical trials comprising 475 patients were performed in the following areas: effects of heparin coating on measures of clinical outcome and memory function (I, II), inflammatory reactions in PSB and its systemic effects after retransfusion using cardiotomy suction or cell salvage (III) and effects of retransfusion of PSB on memory function and release patterns of protein S100B (IV). LÄS MER

5. 4. Enzymes involved in biosynthesis and degradation of heparin-related polysaccharides

   Författare :Dagmar Sandbäck Pikas; Uppsala universitet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; heparin; heparan sulphate; biosynthesis; N-deacetylase N-sulphotransferase; endoglycosidase; heparanase; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

   Sammanfattning : Heparin and heparan sulphate (HS) are structurally related polysaccharides of the glycosaminoglycan type. As the glycan moiety of proteoglycans, they exist covalently linked to various core proteins. LÄS MER

7. 5. Novel chemical and enzymatic routes to the generation of heparin- related polysaccarides

   Författare :Jianhui Rong; Uppsala universitet; []
   Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; heparin; heparan sulphate; biosynthesis; 2-O-sulphotransferase; neo-glycosaminoglycan; conjugation; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

   Sammanfattning : Heparin and heparan sulphate (HS) are structurally related polysaccharides influencing various biological processes. The biological functions of heparin/HS largely depend on interactions between the negatively charged polysaccharide chains and a variety of proteins. LÄS MER