Sökning: "antiretroviral"
Visar resultat 11 - 15 av 152 avhandlingar innehållade ordet antiretroviral.
11. Short modified peptides and their metabolites inhibit HIV replication
Sammanfattning : Several drugs inhibiting the replication of HIV-1, the causative agent of AIDS, are available today. However, HIV-1 treatment is hampered by side effects, poor adherence and development of resistance. LÄS MER
12. Development and Validation of Bioanalytical Methods : Application to Melatonin and Selected Anti-Infective Drugs
Sammanfattning : This thesis describes bioanalytical methods for measuring melatonin and some anti-infective drugs in biological fluids. Solid-phase extraction (SPE) or protein precipitation was used for enrichment and purification of the analytes and Liquid Chromatography (LC) was used to analyze the samples. LÄS MER
13. On HIV-1 infection in the central nervous system
Sammanfattning : HIV-1 (hereafter referred to as HIV) is a neurotropic virus that invades the central nervous system (CNS). The CNS is then susceptible to an acute infection and later to CNS opportunistic diseases and AIDS dementia complex (ADC). HIV does not infect the neurons, and neuropathogenesis is largely mediated by the immune system. LÄS MER
14. The battleground of two Infections and a cancer: Human Papilloma Virus, premalignant lesions of the cervix and their interaction with Human Immunodeficiency Virus in southwestern Nigeria
Sammanfattning : Background: The highest numbers of HIV-infected women are in sub- Saharan Africa, where the natural progression of HIV disease in the absence of treatment results in death before the onset of invasive cervical cancer. With improved access to treatment, several studies outside West Africa demonstrated an increased risk of pre-invasive cervical lesions among HIV-infected women and the positive impact of treatment on the outcome. LÄS MER
15. HIV Persistence and Viral Reservoirs
Sammanfattning : Although antiretroviral therapy (ART) can effectively inhibit replication of human immunodeficiency virus type 1 (HIV-1), the virus is able to persist in cellular and anatomical viral reservoirs. Latently infected resting memory CD4+ T-cells are an important cellular reservoir, and the central nervous system (CNS) an important anatomical reservoir for HIV-1 infection. LÄS MER