Sökning: "CD26"
Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet CD26.
1. Short modified peptides and their metabolites inhibit HIV replication
Sammanfattning : Several drugs inhibiting the replication of HIV-1, the causative agent of AIDS, are available today. However, HIV-1 treatment is hampered by side effects, poor adherence and development of resistance. LÄS MER
2. Immunological and Genetic Markers Predicting Treatment Outcome in Hepatitits C Virus Infection
Sammanfattning : Hepatitis C is a blood-borne infection caused by the hepatitis C virus (HCV). A chronic infection, which develops in most infected subjects, may lead to liver cirrhosis with ensuing liver dysfunction and liver cancer. LÄS MER
3. Immunological studies on anca-associated vasculitis with special reference to T cell activation
Sammanfattning : This thesis focuses on the role of T cells in ANCA-associated vasculitis. We initially investigated activation markers on T cells in patients with Wegener's granulomatosis (WG), microscopic polyangiitis (MPA) and renal limited disease (RLD) and found increased expression indicating continuous activation despite clinical remission. LÄS MER
4. T lymphocyte and NK cell function in pulmonary inflammation in sarcoidosis
Sammanfattning : The focus of this thesis is on the role of T lymphocytes and Natural Killer cells in sarcoidosis, which is an inflammatory interstitial pulmonary disorder of unknown etiology. An accumulation of CD4+ T helper cells in the lungs is a characteristic feature of this disease. LÄS MER
5. T cell antigen receptor usage, phenotype and cytokine production in human diseases
Sammanfattning : T lymphocytes are of critical importance for initiating and controlling immune responses, as the T cell receptor (TCR) for antigen allows a highly specific antigen recognition. Determination of TCR usage and characterization of T cell subsets in different diseases helps us understand the underlying immunopathogenic mechanisms, and may also lead to the development of new therapeutic approaches. LÄS MER