Visar resultat 1 - 5 av 27 avhandlingar innehållade ordet Src-family.
1. Signal Transduction in Focal Cerebral Ischemia : Experimental Studies on VEGF, MAPK and Src family kinases
Sammanfattning : Cerebral ischemia elicits a wide range of events, including complex activation of various intracellular signaling pathways. This study aims to investigate the expression of vascular endothelial growth factor (VEGF) and the activation pattern of mitogen-activated protein kinases (MAPK) in reponse to focal cerebral ischemia. LÄS MER
2. Protein tyrosine kinases in insulin producing cells : Expression and putative importance for beta-cell function
Sammanfattning : Protein tyrosine kinases are of importance for cell replication and differentiation in manysystems. The mechanisms controlling the replication and differentiation of insulin producingcells are unknown. LÄS MER
Sammanfattning : Prion diseases are fatal and incurable spongiform encephalopathies that occur amongst mammals. The central pathological event is the misfolding of the cellular prion protein (PrPC) into an amyloid, neurotoxic isoform called scrapie (PrPSc). PrPSc is the main, or sole, constituent of infectious prions. LÄS MER
Sammanfattning : Crk associated substrate (Cas) is an adaptor protein that becomes phosphorylated upon integrin signaling and influences regulation of cell processes such as migration, proliferation and survival. It consists of multiple domains and regions that can interact with several signaling proteins involved in different signaling pathways. LÄS MER
Sammanfattning : The transcription factor Grainy head (Grh) is conserved from Drosophila to humans. Drosophila Grh plays important roles in epithelial differentiation and regeneration. LÄS MER