Sökning: "Reumatologi och molekylär skelettbiologi"
Visar resultat 11 - 15 av 37 avhandlingar innehållade orden Reumatologi och molekylär skelettbiologi.
11. Joint disease biomarkers - discovery and application
Sammanfattning : Dysregulated cartilage homeostasis, articular cartilage degradation and abnormal bone remodeling are common denominators in joint disease and can lead to severe disability for the patients. The molecular pathways behind the disease pathology can overlap across different joint diseases. LÄS MER
12. Injury-induced activation of vascular smooth muscle cells. Role of specific gene expression and intracellular signalling pathways
Sammanfattning : Migration and proliferation of smooth muscle cells (SMC) are important events in the development of atherosclerosis and restenosis following angioplastic surgery. It is important to gain further knowledge about the mechanisms regulating SMC form and function in order to understand the underlying disease process. LÄS MER
13. Fibromodulin and chondroadherin in connective tissue homeostasis
Sammanfattning : Connective tissue contains a prominent extracellular matrix (ECM), which provides for physiological and mechanical properties. Intra- and inter-molecular interactions between proteins in this ECM provide for the formation of molecular networks. These interactions determine the shape of the tissue as well as cell behavior. LÄS MER
14. Systemic Lupus Erythematosus, with focus on vascular wall changes, cardiac risk-factor awareness and cardiovascular events
Sammanfattning : Systemic Lupus Erythematosus is an autoimmune disease with a wide range of disease manifestations with respect to severity and magnitude of organ involvement. An increased risk of cardiovascular disease (CVD) compared with the general population causes both morbidity and mortality in SLE patients. LÄS MER
15. Team rehabilitation and health care utilization in chronic inflammatory arthritis patients
Sammanfattning : The aim of this thesis was to study outcome and evaluation of rheumatological multidisciplinary team rehabilitation programmes in patients with chronic inflammatory arthritis (CIA); rheumatoid arthritis (RA), ankylosing spondylitis, psoriatic arthritis and other spondyloarthritides, and to analyse health care utilization over the last decade in patients with RA. In Study I the outcome of an 18 days outpatient multidisciplinary team rehabilitation programme in 174 patients with CIA was analysed. LÄS MER