Sökning: "PLS"

Visar resultat 16 - 20 av 144 avhandlingar innehållade ordet PLS.

1. 16. Process analytical methods for monitoring of the film coating on pharmaceutical pellets and tablets using NIR spectrometry and image analysis

   Författare :Martin Andersson; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PLS; PCA; PAC; NIR; chemometrics; moving samples; information depth; release rate; image analysis; near infrared; process analytical chemistry; thickness; coating; film; tablets; Pellets; granules; Analytical chemistry; Analytisk kemi;

   Sammanfattning : Pharmaceutical tablets and pellets are often covered with a coating. There is a need for methods that enable monitoring of the growth of such films during processing. Such analyses can be performed using process analytical chemical methods based on near infrared (NIR) diffuse reflectance spectrometry. It provides with analyses that take only ca. LÄS MER

3. 17. Biocatalysed redox reactions in aqueous and organic media

   Författare :Mats Andersson; Bioteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; PLS; coenzyme regeneration; bioelectrocatalysis; hydrogenase; chloroperoxidase; HLADH; Proteus vulgaris; Alcaligenes eutrophus; artificial electron mediator; D- S _chlorolactic acid; Biotechnology; Bioteknik;

   Sammanfattning : This thesis deals mainly with biocatalysed methods for stereoselective reduction. D-(S)-chlorolactic acid was produced by both microbial and electromicrobial reduction of chloropyruvate using whole cells of Proteus vulgaris and an artificial electron mediator. The electron donor was formate, hydrogen gas or the cathode in an electrochemical cell. LÄS MER

4. 18. Microextraction for usage in environmental monitoring and modelling of nitroaromatic compounds and haloanisoles

   Författare :Sofie Jönsson; Bert van Bavel; Tomas Öberg; Örebro universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PCA; PLS; QSPR; SPME; MEPS; nitroaromatic compounds; TCA; TBA; Chemistry; Kemi; Kemi; Chemistry;

   Sammanfattning : Processes in the environment are often complex and the description and prediction of the behaviour of environmental pollutants requires sophisticated methodology including multidimensional technology. Multivariate statistical methods including principal component analysis (PCA) and partial least squares projection to latent structures (PLS) were used to characterise several nitroaromatic compounds according to a large number of chemical and physical properties. LÄS MER

5. 19. Physico-chemical characteristics and quantitative structure-activity relationships of PCBs

   Författare :Patrik Andersson; Stephen Safe; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; polychlorinated biphenyls; PCBs; physico-chemical properties; statistical design; multivariate; PCA; PLS; biomagnification; BMF; bioassay; CYP1A; SAR; QSAR; REPs; risk assessment; Chemistry; Kemi; Chemistry; Kemi;

   Sammanfattning : The polychlorinated biphenyls (PCBs) comprise a group of 209 congeners varying in the number of chlorine atoms and substitution patterns. These compounds tend to be biomagnified in foodwebs and have been shown to induce an array of effects in exposed organisms. LÄS MER

7. 20. Multivariate methods in tablet formulation

   Författare :Jon Gabrielsson; Michael Sjöström; Svante Wold; Torbjörn Lundstedt; Marc Brown; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; PCA; statistical experimental design; multivariate design; PLS; excipients; direct compression; tablet formulation; robustness testing; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

   Sammanfattning : This thesis describes the application of multivariate methods in a novel approach to the formulation of tablets for direct compression. It begins with a brief historical review, followed by a basic introduction to key aspects of tablet formulation and multivariate data analysis. LÄS MER