Sökning: "Torbjörn Lundstedt"

Hittade 5 avhandlingar innehållade orden Torbjörn Lundstedt.

  1. 1. Multivariate methods in tablet formulation

    Författare :Jon Gabrielsson; Michael Sjöström; Svante Wold; Torbjörn Lundstedt; Marc Brown; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; PCA; statistical experimental design; multivariate design; PLS; excipients; direct compression; tablet formulation; robustness testing; Organisk kemi; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis describes the application of multivariate methods in a novel approach to the formulation of tablets for direct compression. It begins with a brief historical review, followed by a basic introduction to key aspects of tablet formulation and multivariate data analysis. LÄS MER

  3. 2. Metabolic variation in autoimmune diseases

    Författare :Rasmus Kirkegaard Madsen; Johan Trygg; Thomas Moritz; Torbjörn Lundstedt; Matej Oresic; Umeå universitet; []
    Nyckelord :Rheumatoid Arthritis; Diabetes Mellitus type 1; Metabolic Profiling; Metabolomics; Chemometrics; Multivariate Data Analysis; Mass Spectrometry; biologisk kemi; biological chemistry;

    Sammanfattning : The human being and other animals contain immensely complex biochemical processes that govern their function on a cellular level. It is estimated that several thousand small molecules (metabolites) are produced by various biochemical pathways in humans. LÄS MER

  4. 3. Computational Modeling of the AT2 Receptor and AT2 Receptor Ligands : Investigating Ligand Binding, Structure–Activity Relationships, and Receptor-Bound Models

    Författare :Christian Sköld; Anders Karlén; Anders Hallberg; Torbjörn Lundstedt; Tommy Liljefors; Uppsala universitet; []
    Nyckelord :Pharmaceutical chemistry; Angiotensin II; AT1; AT2; SAR; bioactive conformation; turn mimetic; peptidomimetic; DISCO; homology model; 3D-QSAR; CoMFA; Farmaceutisk kemi;

    Sammanfattning : Rational conversion of biologically active peptides to nonpeptide compounds with retained activity is an appealing approach in drug development. One important objective of the work presented in this thesis was to use computational modeling to aid in such a conversion of the peptide angiotensin II (Ang II, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe). LÄS MER

  5. 4. Multivariate data analysis of metabolomic multi-tissue samples

    Författare :Frida Torell; Johan Trygg; Torbjörn Lundstedt; Thomas Moritz; Kate Bennett; Michal Daszykowski; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Multi-tissue metabolomics involves characterisation of the metabolome of several tissue types. The metabolome consists of small chemical entities of low molecular weight called metabolites, which are constantly produced and interchanged through a vast variety of biochemical reactions occurring throughout living organisms. LÄS MER

  7. 5. Den korrekta avvikelsen : vetenskapsanvändning, normalitetssträvan och exkluderande praktiker hos RFSL, 1950-1970

    Författare :Andréaz Wasniowski; Kjell Jonsson; Svante Norrhem; Torbjörn Gustafsson Chorell; Uppsala universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; homosexuality; heteronormativity; gender; sexual deviation; homosexual movement; Daughter of bilitis; Mattachine Society; ONE; Wilhelm Stekel; Richard von Krafft-Ebing; Albert Moll; Wilhelm Reich; Magnus Hirschfeld. Allan Hellman; George Henry; Alfred Kinsey; Sigmund Freud; Ellis Havelock; Jarl Wagner Smitt; Albert von Schrenck-Notzing; Karl Heinrich Ulrichs; RFSL; homosexualitet; heteronormativitet; normer; sexualvetenskap; sexologi; psykoanalys; representationalism; genus; queer; transvestitism; transsexualism; hermafroditism; masochism; sadism; sexualitet; skötsamhet; förbundshistoria; Kinseyrapporten; Wilhelm Stekel; Richard von Krafft-Ebing; Albert Moll; Wilhelm Reich; Magnus Hirschfeld. Allan Hellman; Gunnar Inghe; George Henry; Alfred Kinsey; Vilhelm Lundstedt; Gunnar Nycander; Anton Nyström; Sigmund Freud; Ellis Havelock; Bror Gadelius; Henning Pallesen; Carl Regman; Jarl Wagner Smitt; Albert von Schrenck-Notzing; Karl Heinrich Ulrichs; History of science and ideas; Idé- o lärdomshistoria; Gender studies; Genus; idé- och lärdomshistoria; History Of Sciences and Ideas;

    Sammanfattning : The thesis focuses on the organisation today known as the Swedish Federation for Lesbian, Gay, Bisexual and Transgender Rights (RFSL) and its activities from the founding year 1950 to around 1970. RFSL was the first Swedish organisation that worked for non-heterosexual persons. LÄS MER