Sökning: "Medical Significance"
Visar resultat 1 - 5 av 471 avhandlingar innehållade orden Medical Significance.
1. In Vitro Drug Sensitivity and Apoptosis in Chronic Lymphocytic Leukemia
Sammanfattning : Chronic lymphocytic leukemia (CLL) is a heterogeneous malignancy displaying varying clinical outcome, where molecular markers today can divide patients into prognostic subgroups. Despite the introduction of new agents for treatment, remissions are usually not sustained in CLL and resistance towards treatment can partly be explained by aberrant apoptosis. LÄS MER
2. Functional characterization of the human adenovirus pVII protein and non-coding VA RNAI
Sammanfattning : Human adenovirus (HAdV) is a common pathogen causing a broad spectrum of diseases. HAdV encodes the pVII protein, which is involved in nuclear delivery, protection and expression of viral DNA. To suppress the cellular interferon (IFN) and RNA interference (RNAi) systems, HAdVs encode non-coding virus-associated (VA) RNAs. LÄS MER
3. Characterizing the pancreatic "isletome" : 3D optical imaging to study diabetes
Sammanfattning : The pancreas is a specialised multipurpose organ, that can be separated into two major compartments: endocrine and exocrine. The exocrine part makes up the majority of the organ volume and functions to secrete digestive enzymes into the small intestine. LÄS MER
4. Advancing Clinical Decision Support Using Machine Learning & the Internet of Medical Things : Enhancing COVID-19 & Early Sepsis Detection
Sammanfattning : This thesis presents a critical examination of the positive impact of Machine Learning (ML) and the Internet of Medical Things (IoMT) for advancing the Clinical Decision Support System (CDSS) in the context of COVID-19 and early sepsis detection.It emphasizes the transition towards patient-centric healthcare systems, which necessitate personalized and participatory care—a transition that could be facilitated by these emerging fields. LÄS MER
5. Functional Role of Genetic Polymorphisms Associated with Systemic Lupus Erythematosus
Sammanfattning : Systemic lupus erythematosus (SLE) is a chronic and complex autoimmune disorder characterized by a failure in the mechanism of self-tolerance and production of autoantibodies, potentially affecting any organ in the body. The genetic factors behind the disease have been extensively studied in the past years and to date a list of more than 30 loci have been associated with SLE. LÄS MER