Sökning: "Lena L"

Visar resultat 1 - 5 av 41 avhandlingar innehållade orden Lena L.

  1. 1. Factors modulating neonatal pain responssiveness

    Författare :Lena L Bergqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : To relieve pain in newborn infants, particularly preterm infants, is essential in modern neonatology. However, there are a number of innate difficulties related to pain assessment and pharmacological treatment, which includes in this thesis work. LÄS MER

  3. 2. Macroalgae in the Baltic Sea : responses to low salinity and nutrient enrichment in Ceramium and Fucus

    Författare :Lena Bergström; Lars Ericson; Lena Kautsky; Erik Bonsdorff; Christine A Maggs; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ecology; adaptation; asexual reproduction; Baltic Sea; Gulf of Bothnia; salinity; macroalgae; nutrients; sexual reproduction; stress; Ekologi; Terrestrial; freshwater and marine ecology; Terrestisk; limnisk och marin ekologi; ekologisk botanik; Ecological Botany;

    Sammanfattning : The brackish Baltic Sea is a marginal environment for both marine and freshwater species. The rate of ecological differentiation is presumably high due to strong selection pressure from a gradient of decreasing salinity that has been present in its current state for only about 3 000 years. LÄS MER

  4. 3. Structural and Functional Studies of Peptidyl-prolyl cis-trans isomerase A and 1-deoxy-D-xylulose- 5-phosphate reductoisomerase from Mycobacterium tuberculosis

    Författare :Lena M Henriksson; Torsten Unge; Sherry L. Mowbray; Barbara Seaton; Uppsala universitet; []
    Nyckelord :Molecular biology; Mycobacterium tuberculosis; Rv0009; peptidyl-prolyl cis-trans isomerase; Rv2870c; 1-deoxy-D-xylulose-5-phosphate reductoisomerase; non-mevalonate pathway; DOXP MEP pathway; X-ray crystallography; Molekylärbiologi;

    Sammanfattning : Mycobacterium tuberculosis, the causative pathogen of tuberculosis, currently infects one-third of the world’s population, resulting in two million deaths annually. This clearly shows that tuberculosis is one of the most serious diseases of our times. LÄS MER

  5. 4. Pharmacometric Models for Improved Prediction of Myelosuppression and Treatment Response in Oncology

    Författare :Angelica L Quartino; Mats O Karlsson; Lena E Friberg; Etienne Chatelut; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacometrics; oncology; myelosuppression; chemotherapy; pharmacokinetics; pharmacodynamics; PHARMACY; FARMACI; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

    Sammanfattning : Chemotherapy plays an important role in the treatment of cancer. However, these drugs also cause death of non-malignant cells, resulting in severe side-effects. In addition, drug resistance may exist. Predictive tools for dose and drug selection are therefore warranted. LÄS MER

  7. 5. Heparan Sulfate and Development : A Study of NDST Deficient Mice and Embryonic Stem Cells

    Författare :Katarina Holmborn; Lena Kjellén; Erik Forsberg; Catherine L. Merry; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell and molecular biology; heparan sulfate; proteoglycan; biosynthesis; N-deacetylase N-sulfotransferase; NDST; gene targeting; embryonic development; lung development; mast cells; Cell- och molekylärbiologi;

    Sammanfattning : Heparan sulfate (HS) proteoglycans consist of sulfated HS chains covalently bound to core proteins. They are ubiquitously expressed, on the cell surface and in the extracellular matrix, throughout the body. LÄS MER