Sökning: "Insulin-like peptide 5"

Visar resultat 1 - 5 av 19 avhandlingar innehållade orden Insulin-like peptide 5.

1. 1. Microbial regulation of Insulin-like peptide 5 and its implication on metabolism and bariatric surgery

   Författare :Ying Shiuan Lee; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gut microbiota; gut hormones; Insulin-like peptide 5; bariatric surgery;

   Sammanfattning : The microbial community in our gastrointestinal tract, the gut microbiota, has great impact on our physiology. Particularly, the role for gut microbiota in host health and disease has been associated with modulation of gut hormones which are key players in the regulation of energy homeostasis. LÄS MER

3. 2. Structure and function of relaxins

   Författare :Linda M. Haugaard-Kedström; Johan Rosengren; Torleif Härd; Linnéuniversitetet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; relaxin; insulin-like peptide; peptide hormone; peptide synthesis and NMR; Organic Chemistry; Organisk kemi;

   Sammanfattning : The relaxin/insulin superfamily is a group of peptide hormones that consists of ten members in human, namely relaxins 1-3, insulin-like peptides (INSL) 3-6, insulin and insulin-like growth factors (IGF) I-II. These peptides have various functions in the body, such as regulating growth, blood glucose levels,  collagen metabolism, germ cell maturation and appetite. LÄS MER

4. 3. The insulin-like growth factor system : effects of circulating proteases

   Författare :Sara Gustafsson; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The insulin-like growth factor-I and -II (IGF-I/-II) are peptide hormones important for growth and metabolism. They stimulate cell proliferation and differentiation and inhibit apoptosis. In addition, they have insulin-like effects on glucose and amino acid metabolism. LÄS MER

5. 4. Endogenous hormones in the etiology of ovarian and endometrial cancers

   Författare :Annekatrin Lukanova; Eva Lundin; Pär Stattin; Rudolf Kaaks; Susan E. Hankinson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Public health; ovarian cancer; endometrial cancer; sex-steroid hormones; sex-hormone binding globulin; insulin-like growth factor-I; insulin-like growth factor bidning proteins; C-peptide; Folkhälsomedicin; Public health medicine research areas; Folkhälsomedicinska forskningsområden; epidemiologi; Epidemiology;

   Sammanfattning : The main purpose of this thesis was to examine the relationship of pre-diagnostic circulating levels of sex-steroids (androgens and estrogens), sex hormone binding globuline (SHBG), insulin-like growth factor-I (IGF-I), IGF binding proteins (BP) and C-peptide (as a marker of pancreatic insulin secretion) with risk of ovarian and endometrial cancer. Additionally, the interrelationships of body mass index (BMI), sex-steroids, IGF-I and IGFBP-3 were examined. LÄS MER

7. 5. High-molecular-weight insulin-like growth factor 2 : immunohistochemical, ultrastructural and biochemical findings in insulin cells under normal, diabetic, and neoplastic conditions, and its role in non-islet cell tumour hypoglycaemia

   Författare :Anders Höög; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Insulin-like growth factor-2; IGF-2; islets of Langerhans; B-granules; Diabetes Mellitus type 2; insulinoma; Goto-Kakizaki rat; haemangiopericytoma; ultrastructural immunohistochemistry; gene expression.;

   Sammanfattning : IGF-2 immunoreactive (IR) cells were identified in the normal adult pancreas of man and rat and occurred exclusively in insulin-producing cells. When frozen human pancreatic tissue was extracted and gel-size-separated, a high-molecular-weight (HMW) IGF-2 peptide could be identified. LÄS MER