Sökning: "Fatima Pedrosa Domellöf"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Fatima Pedrosa Domellöf.
1. Laminins and alpha11 integrin in the human eye : importance in development and disease
Sammanfattning : The extracellular matrix (ECM) offers a protective shelter for cells and provides signaling paths important for cell to cell communication. ECM consists of basement membranes (BM) and interstitial matrix. BMs provide mechanical support for parenchymal cells, influence cell proliferation, survival, migration and differentiation. LÄS MER
2. Genetic studies of zebrafish muscles : clues to protection in muscle disease
Sammanfattning : Muscular dystrophies (MDs) are caused by dysregulation of over 40 proteins but commonly share features of muscle weakness, myofiber death and regeneration, loss of ambulation and premature death. A MD involves a broken link anywhere in the connection from extracellular matrix through the sarcolemma to the sarcomere. LÄS MER
3. Applying proteomics and metabolomics for studying human skeletal muscle with a focus on chronic trapezius myalgia
Sammanfattning : Work related musculoskeletal disorders are the dominating causes of reported ill-health in industrialized countries. These chronic pain conditions are one of the most costly public health problems in Europe and North America. LÄS MER
4. Human Skeletal Muscle : a basic proteomic approach
Sammanfattning : The trapezius is a muscle of clinical interest due to its susceptibility to chronic work related musculoslteletal disorders. The mechanisms underlying these conditions are not fully understood. LÄS MER
5. A Muscle Perspective on the Pathophysiology of Amyotrophic Lateral Sclerosis : Differences between extraocular and limb muscles
Sammanfattning : Background: Amyotrophic lateral sclerosis (ALS) is a late-onset progressive neurodegenerative disorder. ALS has been traditionally believed to be primarily a motor neuron disease. LÄS MER