Sökning: "ophthalmology"

Visar resultat 1 - 5 av 114 avhandlingar innehållade ordet ophthalmology.

1. 1. Genetic studies of zebrafish muscles : clues to protection in muscle disease

   Författare :Nils Dennhag; Fatima Pedrosa Domellöf; Jonas von Hofsten; Tatjana Haitina; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; zebrafish; muscle; extraocular muscles; intermediate filaments; bioinformatics; genetics; CRISPR Cas9; oftalmiatrik; ophthalmology; cellforskning; cell research;

   Sammanfattning : Muscular dystrophies (MDs) are caused by dysregulation of over 40 proteins but commonly share features of muscle weakness, myofiber death and regeneration, loss of ambulation and premature death. A MD involves a broken link anywhere in the connection from extracellular matrix through the sarcolemma to the sarcomere. LÄS MER

3. 2. Laser treatment in glaucoma : efficacy and safety

   Författare :Erika Rasmuson; Gauti Jóhannesson; Christina Linden; Björn Lundberg; Mika Harju; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glaucoma; laser treatment; intraocular pressure; glaucoma treatment; glaukom; laserbehandling; ögontryck; glaukombehandling; oftalmiatrik; ophthalmology; oftalmiatrik; ophthalmology;

   Sammanfattning : Glaucoma is a progressive optic neuropathy and the major cause of irreversible blindness worldwide. Although the pathogenesis of glaucoma is not completely understood, the most important risk factor for development and progression of the disease is an elevated intraocular pressure (IOP). LÄS MER

4. 3. Fuchs’ endothelial corneal dystrophy : Genetic aetiology and as a risk factor in cataract surgery

   Författare :Andreas Viberg; Berit Byström; Irina Golovleva; Patrik Danielson; Madeleine Zetterberg; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fuchs’ endothelial corneal dystrophy; genetics; TCF4; trinucleotide repeat disorder; registry-based study; cataract surgery; outcome; PROM; corneal transplantation; dense cataract; posterior capsule rupture; oftalmiatrik; ophthalmology; Clinical Genetics; klinisk genetik;

   Sammanfattning : Fuchs’ endothelial corneal dystrophy (FECD) is a bilateral, often hereditary degenerative corneal disease, in which the disrupted endothelial cell function causes corneal swelling and reduced vision. An early clinical sign of FECD is corneal guttata, an irregularity of the endothelial layer. LÄS MER

5. 4. Aniridia-related keratopathy : structural changes, signaling pathways and clinical aspects

   Författare :André Vicente; Fatima Pedrosa Domellöf; Berit Byström; Luis Abegão Pinto; Jing-Xia Liu; Anders Ivarsen; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aniridia; aniridia-related keratopathy; PAX6; keratoplasty; fetal cornea; Notch1; Wnt; sonic hedgehog; mTOR; keratocyte; oftalmiatrik; ophthalmology;

   Sammanfattning : Aniridia is a congenital autosomal dominant, bilateral, panocular condition, caused by haploinsufficiency of the Pax6 transcription factor. Aniridia-related keratopathy (ARK) significantly affects vision and quality of life in these patients. LÄS MER

7. 5. Fetal Alcohol Spectrum Disorders in Children and Young Adults with an emphasis on ophthalmology

   Författare :Emelie Gyllencreutz; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fetal Alcohol Syndrome; Optic Nerve; Optical Coherence Tomography; Strabismus; Vision; Visual Perception; Quality of Life;

   Sammanfattning : Introduction: Fetal alcohol spectrum disorders (FASD) are a group of disorders caused by prenatal alcohol exposure (PAE). The most severe and most studied FASD condition is fetal alcohol syndrome. Other conditions include partial fetal alcohol syndrome and alcohol-related neurodevelopmental disorder. LÄS MER