Sökning: "Cancer ECM"
Visar resultat 1 - 5 av 64 avhandlingar innehållade orden Cancer ECM.
1. Type IV collagen in breast and colorectal cancer : a potential biomarker of metastatic disease
Sammanfattning : Background: Metastatic colorectal cancer (mCRC) and metastatic breast cancer (mBC) are two leading causes of cancer-related mortality worldwide. Early detection of metastatic disease is critical, and sensitive, easily accessed and cost-effective biomarkers that can diagnose mBC and mCRC at an early stage would have high clinical value. LÄS MER
2. The identification and functional evaluation of novel cancer-associated fibroblast subtypes and matrisome proteins in pancreatic cancer
Sammanfattning : Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy characterized by an extensive desmoplastic stroma. The stroma is the site of intricate communication between malignant cells and their surrounding environment. LÄS MER
3. Breast Cancer Prevention – lifestyle modifications or targeted interventions?
Sammanfattning : Breast cancer is now the most frequently diagnosed cancer in the world. Breast cancer prevention has gained increasing attention due to increasing breast cancer incidence rates in the West and can be actualized through lifestyle modifications or targeted interventions. LÄS MER
4. Role of Wnt-5a in breast cancer
Sammanfattning : Breast cancer is one of the most common cancer forms in the industrialized world. Only in Sweden, nearly 6000 women are diagnosed with breast cancer each year and 1/3 of them eventually succumb to the disease. LÄS MER
5. Crosstalk between colorectal cancer cells and tumour-associated macrophages
Sammanfattning : Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of death from cancer worldwide. People suffering from inflammatory bowel disease, such as Crohns’ disease and ulcerative colitis, are at an increased risk of developing CRC. The development of CRC is highly influenced by the tumour microenvironment. LÄS MER