Sökning: "CHONDROITIN"

Visar resultat 11 - 15 av 54 avhandlingar innehållade ordet CHONDROITIN.

  1. 11. Interactions between herpes simplex virus type 1 glycoprotein C and cell surface glycosaminoglycans

    Författare :Kristina Mårdberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Herpes simplex virus-1; glycoprotein C; virus receptor; glycosaminoglycans; heparan sulfate; chondroitin sulfate;

    Sammanfattning : The cell surface glycosaminoglycan (GAG) heparan sulfate (HS) serves as an initial receptor for herpes simplex virus type 1 (HSV-1) and virus attachment to the HS molecule is mediated by the envelope glycoprotein C (gC). In the first part of this thesis, we aimed to define the HS-binding domain of viral gC. LÄS MER

  3. 12. Structural and Functional Analyses of Xyloside-primed Glycosaminoglycans

    Författare :Andrea Persson; Glykobiologigruppen; []
    Nyckelord :Glycosaminoglycan; Xyloside; Chondroitin sulfate; Dermatan sulfate; Heparan sulfate; Proteoglycan; Cancer;

    Sammanfattning : Glycosaminoglycans (GAGs) are polysaccharides produced by essentially all mammalian cells. Due to their enormous structural diversity, they are involved in many biological processes both in health and disease, including all stages of tumor progression. LÄS MER

  4. 13. Brittlestars Galactosaminoglycans and Tools to Study their Structure

    Författare :Ramesh Babu Namburi; Dorothe Spillmann; Lena Kjellén; Ulf Lindahl; Clare Hughes; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Chondroitin sulfate; Brittlestars; Gut bacteria; H. bizzozeronii; B.thetaiotaomicron; Biokemi; Biochemistry; Mikrobiologi; Microbiology; Molecular Biology; Molekylärbiologi;

    Sammanfattning : In all living organisms, biological activities such as proper functioning and co-ordination of different organs will depend on different cells and molecular interactions. In some organisms the loss of functional organs or damage of organs can be lethal, whereas in others a special process called regeneration can retrieve lost organs. LÄS MER

  5. 14. Glycosaminoglycan Biosynthesis in Zebrafish

    Författare :Beata Filipek-Górniok; Lena Kjellén; Johan Ledin; Kay Grobe; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Heparan sulfate; chondroitin dermatan sulfate; biosynthesis; development; N-deacetylase N-sulfotransferase; glycosyltransferases; morpholino; CRISPR-Cas9;

    Sammanfattning : Proteoglycans (PGs) are composed of highly sulfated glycosaminoglycans chains (GAGs) attached to specific core proteins. They are present in extracellular matrices, on the cell surface and in storage granules of hematopoietic cells. LÄS MER

  7. 15. Interactions between platelets and complement with implications for the regulation at surfaces

    Författare :Per H. Nilsson; Kristina Nilsson Ekdahl; John Lambris; Ian Nicholls; Berhane Ghebrehiwet; Linnéuniversitetet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; complement system activation; regulation ; platelets activation; regulation ; biomaterials; biocompatibility; chondroitin sulfate-A; apyrase; C1q; C3; factor H; C4BP; ADP; Biomedical Sciences; Biomedicinsk vetenskap;

    Sammanfattning : Disturbances of host integrity have the potential to evoke activation of innate immunologic and hemostatic protection mechanisms in blood. Irrespective of whether the activating stimulus is typically immunogenic or thrombotic, it will generally affect both the complement system and platelets to a certain degree. LÄS MER