Sökning: "CD25 regulatory T cells"

Visar resultat 1 - 5 av 47 avhandlingar innehållade orden CD25 regulatory T cells.

  1. 1. T Regulatory Cells – Friends or Foes?

    Författare :Camilla Lindqvist; Angelica Loskog; Thomas Tötterman; Vivianne Malmström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Treg; T regulatory cell; FoxP3; CD25; CLL; B-cell lymphoma; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : T regulatory cells (Tregs) have been extensively studied in patients with cancer or autoimmunity. These cells hamper the immune system’s ability to clear tumor cells in cancer patients. In autoimmune diseases, on the other hand, they are not able to restrain autoreactive immune responses. LÄS MER

  2. 2. Studies on the function of CD4CD25 regulatory T cells: An in vitro approach

    Författare :Lukas Cederbom; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; CD152; Costimulation; Dendritic cells; Regulatory T cells; CD4 CD25 ; serology; transplantation; Immunologi; serologi;

    Sammanfattning : Immunological self-tolerance is a state of the whole organism where deleterious responses are either avoided or regulated. Breaking of immunological tolerance will lead to autoimmune disease or chronic inflammatory conditions. LÄS MER

  3. 3. T cells in chronic obstructive pulmonary disease

    Författare :Ester Roos-Engstrand; Anders Blomberg; Anders Bucht; Annelie F Behndig; Magnus Sköld; Claes-Göran Löfdahl; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway epithelium; bronchoscopy; bronchoalveolar lavage; endobronchial mucosal biopsies; inflammation; flow cytometry; T lymphocytes; CD25; CD127; FoxP3; Lung diseases; Lungsjukdomar; lungmedicin; Lung Medicine;

    Sammanfattning : Background: Tobacco smoking is the main cause of chronic obstructive pulmonary disease, COPD, but the mechanisms by which cigarette smoke induces COPD are still elusive. T lymphocytes have been implicated in the pathogenesis of the disease, but their role in the airway inflammation in COPD is not fully understood. LÄS MER

  4. 4. CD25+CD4+ regulatory T cells in rheumatic disease

    Författare :Duojia Cao; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Human; rheumatic disease; synovial fluid; regulatory T cells; FOXP3; suppression; tolerance; autoimmunity;

    Sammanfattning : CD25+CD4+ T cells represent a unique cell lineage of thymus derived naturally occurring regulatory T cells. The gene Foxp3 (mouse)/ FOXP3(human) is strictly related to their generation in the thymus and their regulatory function in the periphery. LÄS MER

  5. 5. CD4+CD25+ T regulatory cells in multiple sclerosis

    Författare :Prabhakar Putheti; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) is a chronic, inflammatory, and demyelinating disease of the central nervous system (CNS), which is likely to be mediated by autoaggressive immunity. Treatments of MS that may beneficially influence the disease course consist of Avonex (interferon-beta; IFN-beta), and Copaxone (glatiramer acetate; GA). LÄS MER