Sökning: "B-cell lymphoma"

Visar resultat 1 - 5 av 110 avhandlingar innehållade orden B-cell lymphoma.

  1. 1. Protein kinases and phosphatases in B-cell lymphoma

    Detta är en avhandling från Inst för Laboratoriemedicin, Avd för tumörbiologi, Malmö Universitetssjukhus, Lunds Universitet

    Författare :Marie Fridberg; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HePTP; PTEN; PKC-beta 2; B-cell; lymphoma; kinases; ZAP70; phosphatase; SHP2;

    Sammanfattning : Around 2000 persons are diagnosed with lymphoma in Sweden each year. There are many subgroups described for this form of cancer and the great majority is derived from B-cells. The most common subgroup is Diffuse large B-cell lymphoma (DLBCL), a highly aggressive disease where only half of the patients are cured. LÄS MER

  2. 2. Aggressive B-cell Lymphomas Studies of Treatment, FDG-PET Evaluation and Prognostic Factors

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Magdalena Adde; Uppsala universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi; Oncology; Onkologi;

    Sammanfattning : To improve outcome in young, high-risk lymphoma patients, treatment was intensified, adding etoposide and rituximab to standard CHOP treatment. Granulocyte-colony stimulating factor (G-CSF) enabled treatment bi-weekly. Results were promising: overall (OS) and event-free survival (EFS) 79% and 60% respectively, median follow up 27 months. LÄS MER

  3. 3. Burkitt lymphoma and diffuse large B-cell lymphoma – therapeutic strategies and pathogenetic mechanisms

    Detta är en avhandling från Lund University, Faculty of Medicine

    Författare :Tove Wästerlid; Lunds universitet.; Lund University.; Lunds universitet.; Lund University.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Burkitt Lymphoma; Chemotherapy; SOX11; Diffuse large B-cell lymphoma; Prognostic factors; Rituximab;

    Sammanfattning : Burkitt lymphoma (BL) is a rare, aggressive disorder constituting 1% of all non-Hodgkin lymphoma. Diffuse large B-cell lymphoma (DLBCL) is more common, accounting for 30% of malignant lymphoma. Standard treatment for adult BL and for certain subgroups of patients with DLBCL remains to be defined due to paucity of randomised trials performed. LÄS MER

  4. 4. Immunoglobulin Gene Analysis in Different B cell Lymphomas With Focus on Cellular Origin and Antigen Selection

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mia Thorsélius; Uppsala universitet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; B cell lymphoma; Immunoglobulin; V gene; somatic hypermutation; antigen selection; quantitative PCR; Genetik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik;

    Sammanfattning : B cell lymphoma (BCL) comprises a biologically and clinically heterogeneous group of tumors deriving from different stages of B cell development. The immunoglobulin (Ig) variable heavy chain (VH) gene rearrangement is unique for each BCL and can be used to reveal cellular origin, to study signs of antigen selection and to quantify tumor cell load. LÄS MER

  5. 5. Molecular Characterization of Diffuse Large B-cell Lymphoma and Aspects of Transformation

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mattias Berglund; Uppsala universitet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Diffuse large B-cell lymphoma; Hodgkin lymphoma; follicular lymphoma; transformation; comparative genomic hybridization; prognosis; Onkologi; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi;

    Sammanfattning : Lymphomas are a heterogeneous group of neoplasias originating from B- or T-lymphocytes. In this thesis, we determined the genetic and immunophenotypic characterization of DLBCL and their prognostic impact. LÄS MER