Sökning: "18-F"

Hittade 4 avhandlingar innehållade ordet 18-F.

  1. 1. A clinical positron emission tomography facility. 2-[18-F]FDG studies: development and results

    Författare :Tomas G Ohlsson; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radiology; Clinical physics; head and neck cancer; monitoring therapy effect; quantification; normalization; 511 keV SPECT; rotating PET scanner; 2-[18-F]FDG; isotope production; 18-F; PET; positron emission tomography; tomography; medical instrumentation; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

    Sammanfattning : Positron emission tomography (PET) is a tracer technique used for quantitative in vivo studies of physiological and biochemical processes. Because of the use of positron-emitting radionuclides such as 11-C, 13-N, 15-O and 18-F, which are isotopes of the biologically ubiquitous elements, it is possible to label radiopharmaceuticals which trace biochemical processes precisely. LÄS MER

  2. 2. Development of novel fluorine-18 labeled PET radioligands for monoamine oxidase B (MAO-B)

    Författare :Sangram Nag; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selectiv e and irreversible MAO-B inhibitors such as L -deprenyl and rasagiline are clinically used for the t reatment of psychiatric and neurological disorders. LÄS MER

  3. 3. On the Design of Affibody Molecules for Radiolabeling and In Vivo Molecular Imaging

    Författare :Daniel Rosik; Amelie Eriksson Karlström; Christian Heinis; KTH; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Affibody molecule; AC DC; radionuclide molecular imaging; HER2; SPECT; PET; biodistribution; peptide synthesis; radiolabeling; SRA - Molekylär biovetenskap; SRA - Molecular Bioscience;

    Sammanfattning : Affibody molecules have lately shown great potential as tools for in vivo molecular imaging. These small, 3-helical bundles, with their highly stable protein scaffold, are well suited for the often harsh conditions of radiolabeling. LÄS MER

  4. 4. Deciphering the role of 27-hydroxycholesterol in neurodegeneration

    Författare :Muhammad Al Mustafa Ismail; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Cholesterol is constantly attributed to neurodegenerative diseases including Alzheimer’s disease (AD). This is due to the association of high blood cholesterol and the consequences of cholesterol metabolism in these conditions. LÄS MER