Sökning: "SRA - Molecular Bioscience"
Visar resultat 1 - 5 av 21 avhandlingar innehållade orden SRA - Molecular Bioscience.
1. Engineering of Affibody molecules for Radionuclide Molecular Imaging and Intracellular Targeting
Sammanfattning : Affibody molecules are small (7 kDa) affinity proteins of non-immunoglobulin origin that have been generated to specifically interact with a large number of clinically important molecular targets.In this thesis, Affibody molecules have been employed as tracers for radionuclide molecular imaging of HER2- and IGF-1R-expressing tumors, paper I-IV, and for surface knock-down of EGFR, paper V. LÄS MER
2. On the Design of Affibody Molecules for Radiolabeling and In Vivo Molecular Imaging
Sammanfattning : Affibody molecules have lately shown great potential as tools for in vivo molecular imaging. These small, 3-helical bundles, with their highly stable protein scaffold, are well suited for the often harsh conditions of radiolabeling. LÄS MER
3. Theoretical Characterization of Functional Molecular Materials
Sammanfattning : Nowadays, material, energy and information technologies are three pillar industries. The materials that have close relation with our life have also been the foundation for the development of energy and information technologies. LÄS MER
4. An albumin-binding domain as a scaffold for bispecific affinity proteins
Sammanfattning : Protein engineering and in vitro selection systems are powerful methods to generate binding proteins. In nature, antibodies are the primary affinity proteins and their usefulness has led to a widespread use both in basic and applied research. LÄS MER
5. Strategies for the Discovery of Carbohydrate-Active Enzymes from Environmental Bacteria
Sammanfattning : The focus of this thesis is a comparative study of approaches in discovery of carbohydrate-active enzymes (CAZymes). CAZymes synthesise, bind to, and degrade all the multitude of carbohydrates found in nature. LÄS MER
