Sökning: "Äldre för mycket läkemedel"

Visar resultat 16 - 20 av 22 avhandlingar innehållade orden Äldre för mycket läkemedel.

1. 16. Effect of Drugs on Rabbit Retina

   Författare :Anna Cardiakidis Myers; Lund Oftalmologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug toxicity; electroretinography; histopathology; intravitreal injection; rifabutin; anti-VEGF; triamcinolone; benzyl alcohol; anti-TNF-alpha; adalimumab;

   Sammanfattning : The adverse effects of drugs in the eye are not easily detected, and the underlying pathogenesis not fully understood. The effects of four different kinds of drugs have been investigated in the rabbit eye, using electroretinography, ocular examination and histochemical methods. LÄS MER

3. 17. Laser Spectroscopy in Scattering Media for Biological and Medical Applications

   Författare :Linda Persson; Atomfysik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Instrumentation technology; Mät- och instrumenteringsteknik; Atom- och molekylärfysik; Atomic and molecular physics; Fysik; Physics; Monte Carlo simulations; Biomedical Optics; Scattering media; Gas measurements; Near infrared spectroscopy; Diode laser spectroscopy; Absorption spectroscopy;

   Sammanfattning : Tunable diode laser absorption spectroscopy can be utilised for gas detection in biological and medical applications. The common approach is to analyse transmitted light according to the Beer-Lambertian law. LÄS MER

4. 18. Health economics and its measures in rheumatoid arthritis

   Författare :Johan Karlsson; Reumatologi och molekylär skelettbiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cost-utility analysis; Cost-of-illness; Quality of life; EuroQol 5-Dimensions; Antirheumatic agents; TNF inhibition; Outcome assessment; Disease activity; Disability; Health economics; Rheumatoid arthritis;

   Sammanfattning : Objectives: To study: (I) the impact on cost-utility analyses of applying different national EuroQol 5-Dimensions (EQ-5D) preference sets; (II and III) whether, in methotrexate-refractory, early rheumatoid arthritis (RA), the addition of infliximab results in superior health-related quality of life (HRQoL) and may be considered cost-effective, as compared to adding sulfasalazine and hydroxychloroquine; (IV) how costs relate to disability (measured by the health-assessment questionnaire, HAQ), disease activity (28-joint disease activity score, DAS28) and HRQoL (EQ-5D) in RA. Methods: In the observational SSATG register, one-year quality-adjusted life-year (QALY) accumulation of two interventions was compared according to the UK, US, or Danish EQ-5D preference sets. LÄS MER

5. 19. Acute Mastoiditis in Children – A National Study in Sweden

   Författare :Frida Enoksson; Lund näs- och halssjukdomar Öron-; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pneumococcal conjugate vaccine; surgical treatment; guidelines; paediatric; acute mastoiditis;

   Sammanfattning : One of the greatest threats to society today is the development of bacterial resistance to antibiotics. It is commonly accepted that this is mainly due to the use of antibiotics. Acute otitis media (AOM) is responsible for the highest number of antibiotic prescriptions to children although it is in most cases a self-limiting disease. LÄS MER

7. 20. Endothelin receptor changes during inflammation in the lung

   Författare :Bengt Granström; Lund Pediatrik; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; Upregulation; Smooth muscle cells; Smoking; Sephadex; Remodeling; Rat; mRNA; Human; ETB receptor; ETA receptor; Lung; Endothelin; Asthma bronchiale; Contraction;

   Sammanfattning : Endothelin-1 (ET-1) is an extremely potent smooth muscle spasmogen well known from the vascular system but also active within the airways. The importance of its proinflammatory and co-mitogenic properties has become increasingly evident, the endothelin system also having been shown to mimic the signal features of asthma, COPD and other pulmonary diseases. LÄS MER