Sökning: "adalimumab"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet adalimumab.

  1. 1. Effect of Drugs on Rabbit Retina

    Författare :Anna Cardiakidis Myers; Lund Oftalmologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Drug toxicity; electroretinography; histopathology; intravitreal injection; rifabutin; anti-VEGF; triamcinolone; benzyl alcohol; anti-TNF-alpha; adalimumab;

    Sammanfattning : The adverse effects of drugs in the eye are not easily detected, and the underlying pathogenesis not fully understood. The effects of four different kinds of drugs have been investigated in the rabbit eye, using electroretinography, ocular examination and histochemical methods. LÄS MER

  3. 2. Engineering Yeast for the Production of Biologicals

    Författare :Veronica Gast; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; biopharmaceuticals; genome-scale models.; kinase Gcn2; Recombinant protein production; proteases; Saccharomyces cerevisiae; biologicals;

    Sammanfattning : The market for biopharmaceutical proteins, or biologicals, has been expanding rapidly over the last decades and its value was estimated in 2020 to exceed 300 billion US dollars. Efficient cell factories that produce the biologicals fulfill an essential role within this industry. LÄS MER

  4. 3. Generating Affinity Proteins for Biotechnological, Diagnostic and Therapeutic Applications

    Författare :Feifan Yu; Per-Åke Nygren; Lynne Regan; KTH; []
    Nyckelord :Protein engineering; Bioteknologi; Biotechnology;

    Sammanfattning : Protein engineering is a powerful tool to modify proteins to generate novel and desired properties that could be applied in biotechnological, diagnostics and therapeutic areas. In this thesis, both rational design and library based engineering principles have been exploited to develop affinity proteins with desired traits. LÄS MER

  5. 4. Clinical and epidemiologic aspects of Rheumatoid Arthritis. Special emphasis on cardiovascular outcome and risk factors

    Författare :Ulf Bergström; Internmedicin - epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rheumatoid arthritis; Cardiovascular disease and Risk factors;

    Sammanfattning : Rheumatoid arthritis (RA) is a systemic disease, with an increased risk of co-morbidity from cardiovascular disease (CVD), in particular among those with severe disease. Environmental risk factors are of potential interest for both prevention and treatment of RA. LÄS MER

  7. 5. Psoriasis : observational studies on clinical course, economic burden and treatment

    Författare :Axel Svedbom; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Better understanding of long-term prognosis, clinical course, comorbidities, economic burden, and treatment of psoriasis, can improve care of patients with the disease and may inform decisions on resource allocation, benefitting not only patients but also the society in general. The Stockholm Psoriasis Cohort (SPC), Study 1, was initiated to describe the clinical course or psoriasis. LÄS MER