Sökning: "Sephadex"

Visar resultat 1 - 5 av 7 avhandlingar innehållade ordet Sephadex.

  1. 1. Uridine, 4-thiouridine and isomaltitol in an asthma-like model : Anti-inflammatory and modulating effects

    Författare :Chamilly Evaldsson; Srinivas Uppugunduri; Margareta Linden; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Uridine; asthma; 4-thiouridine; isomaltitol; isomalt; inflammation; eosinophilia; Sephadex; animal model; rat; Pharmaceutical pharmacology; Farmaceutisk farmakologi; MEDICINE; MEDICIN; Lung diseases; Lungsjukdomar;

    Sammanfattning : In chronic inflammatory diseases like asthma or rheumatoid arthritis, erroneous and exaggerated accumulation of leukocytes in a tissue inadvertently causes the body harm. Several efficient anti-inflammatory drugs exist, for example corticosteroids and cyclo-oxygenase inhibitors. LÄS MER

  3. 2. Endothelin receptor changes during inflammation in the lung

    Författare :Bengt Granström; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Andningsorganen; Respiratory system; Upregulation; Smooth muscle cells; Smoking; Sephadex; Remodeling; Rat; mRNA; Human; ETB receptor; ETA receptor; Lung; Endothelin; Asthma bronchiale; Contraction;

    Sammanfattning : Endothelin-1 (ET-1) is an extremely potent smooth muscle spasmogen well known from the vascular system but also active within the airways. The importance of its proinflammatory and co-mitogenic properties has become increasingly evident, the endothelin system also having been shown to mimic the signal features of asthma, COPD and other pulmonary diseases. LÄS MER

  4. 3. Studies of the Elemental Composition of Airway Surface Liquid with Relevance to Cystic Fibrosis

    Författare :Viengphet Vanthanouvong; Godfried M. Roomans; Isabelle Sermet-Gaudelus; Uppsala universitet; []
    Nyckelord :Anatomy; airway surface liquid; cystic fibrosis; Na; K; Cl; X-ray microanalysis; Anatomi;

    Sammanfattning : Cystic fibrosis (CF) is an inherited disease with symptoms mainly in the respiratory tract. The airway epithelium is covered with a thin layer of fluid, the airway surface liquid (ASL). The volume and composition of ASL are important in the pathogenesis of cystic fibrosis. The composition of ASL was determined. LÄS MER

  5. 4. Studies on Airway Surface Liquid in Connection with Cystic Fibrosis

    Författare :Inna Kozlova; Godfried Roomans; Anca Dragomir; Marieann Högman; Isabelle Sermet-Gaudelus; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cystic fibrosis; CFTR; airway surface liquid; ion content; anesthesia; mist tent therapy; Pseudomonas aeruginosa infection; Cell biology; Cellbiologi;

    Sammanfattning : Cystic fibrosis (CF) is one of the most common fatal inherited diseases, most prevalent among Caucasians. CF is caused by a mutation in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR), which helps to create sweat, digestive juices, and airway surface liquid (ASL). LÄS MER

  7. 5. Mammalian brain acetylcholinesterase : a study of its solubilization, purification, molecular state and interactions with cholinergic ligands including an endogenous modulator

    Författare :Bertil Niklasson; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Affinity chromatography; caudate nucleus; acetylcholinesterase; tetracaine; décaméthonium; d-tubocurarine; edrophonium; fluoride ion; hysteric properties; endogenous ligands to AChE;

    Sammanfattning : Membrane bound AChE from calf brain caudate nucleus was solubilized by use of ion-free media in presence of 10~ M EDTA and 10“5M tetracaine. The irreversible release of AChE was more effectively inhibited by divalent ions compared to monovalent ions added to the medium. LÄS MER